Paper Tim Kuenne (stan Brouns lab) published in Molecular Cell

News - 23 September 2016 - webredactie-bn

The paper describes that CRISPR systems cleverly couple target interference to CRISPR memory update.

The Cas3 nuclease fragments invader DNA into pieces of near-spacer length enriched for PAM sequences on 30 ends to form spacer precursors.

 

Read the paper here.