A boost of €4,1M for joint proton therapy research TU Delft, Erasmus MC and LUMC
The next round of funding has been awarded to 13 researchers within the HollandPTC R&D consortium. All awarded projects are collaborations between 2 or 3 centres.
Marco van Vulpen, professor at TU Delft, Erasmus University Roterdam and Leiden University and medical director of the HollandPTC R&D programme board emphasizes: “It is of great value for the research to bring people from different backgrounds together. We’ve organized HollandPTC around the principle of collaboration and are very happy with the collaboration that we see in the awarded projects. We congratulate the researchers with their grant and look forward to working together.”
The grants are awarded to:
Influence of intrinsic biological variability on the outcome of proton radiotherapy in head and neck cancer.
To identify biological factors that influence the outcomes of proton radiotherapy in head and neck squamous cell carcinoma and use them to develop a predictive framework to estimate cellular/tissue response as a function of linear energy transfer (LET) and dose (rate).
Elucidating mechanisms of proton-induced DNA damage response and molecular signatures to enhance tumor control (PROTON-DDR).
To obtain a biological rationale to further optimize proton therapy, in particular for head & neck cancers.
Human-centric AI for contouring in head-and-neck cancer therapy.
To initiate a research program targeted at the development, implementation, and evaluation of human-centric AI and man-machine interaction for highly efficient re-contouring and quality assurance (QA) in head-and-neck cancer.
On-line adaptive proton therapy for cervical cancer to reduce the impact on morbidity and the immune system (PROTECT).
To reduce radiotherapy-related morbidity in women with locally advanced cervical cancer.
Fully-automated multi-criterial planning for intensity-modulated proton therapy (IMPT) for clinical practice (AUTOPT).
The development and validation of a system for fully automated multi-criterial intensity-modulated proton therapy (IMPT) planning, including options for beam angle selection.