Dr.ir. Alfred C. Schouten
My research focuses on methods and devices to assess and understand neuromuscular control in both healthy subjects and patients with neurological dysfunction. Key is the use of force-controlled robotic manipulators, neuromuscular modelling, and closed-loop system identification techniques to untangle the human motor control system.
Since my PhD I have developed system identification techniques that enable to quantify the contributions of different feedback pathways. My research resulted in a unique method that can distinguish and quantify the position, velocity and force feedback gains simultaneously. The key concept is the use of force-controlled robotic manipulators which allow for natural movement. Together with medical specialist from academic medical centers (LUMC, AMC, ErasmusMC) we apply the methodology to get insight in neurological dysfunction and working to use these manipulators as diagnostic tools.
Recent years I started to apply the methodology of perturbations and closed-loop system identification to understand the cortical contribution to human motor control. Very recently we demonstrated that the cortico-muscular coherence, a measure for the functional connectivity between the brain and muscles, increases with external perturbations.
Born: October 22, 1972 in Dordrecht, The Netherlands.
- Associate professor (0.8 fte) at the Delft University of Technology, Faculty of Mechanical Engineering, Department of Biomechanical Engineering, since 2012.
- Associate professor (0.2 fte) at the University of Twente, Faculty of Engineering Technology, Department of Biomechanical Engineering, since 2012.
- Assistant professor (0.8 fte) at the Delft University of Technology, Faculty of Mechanical Engineering, Department of Biomechanical Engineering (2007-2012).
- Assistant professor (0.2 fte) at the University of Twente, Faculty of Engineering Technology, Department of Biomechanical Engineering (2007-2012).
- Postdoc at the Delft University of Technology, Mechanical Engineering, Biomechanical Engineering (2004-2007).
- PhD. student at the Delft University of Technology, Mechanical Engineering, Man-Machine Systems (1999-2004).
- MSc. student at the Delft University of Technology, Mechanical Engineering, Man-Machine Systems (1995-1999).
- BSc. student at the HTS Dordrecht, Mechanical Engineering (1991-1995).
- HAVO (high school) at Krimpenerwaard college Krimpen a/d IJssel (1985-1991).
see : Neuro Muscular Control
- Schouten AC (2004) Proprioceptive reflexes and neurological disorders. PhD thesis, Delft University of Technology, Delft, the Netherlands, ISBN 90-77595-41-4 ( pdf 2290kb) .
- Mugge W, Schuurmans J, Schouten AC, van der Helm FCT (2009) Sensory weighting of force and position feedback in human motor control tasks. Journal of Neuroscience 29:5476-5482.
- Schuurmans J, de Vlugt E, Schouten AC, Meskers CGM, de Groot JH, van der Helm FCT (2009). The monosynaptic Ia afferent pathway can largely explain the stretch duration effect of the long latency M2 response. Exp Brain Res 193:491-500.
- Meskers CGM, Schouten AC, de Groot JH, de Vlugt E, van Hilten JJ, van der Helm FCT, Arendzen JH (2009) Muscle weakness and lack of reflex gain adaptation predominate during post-stroke posture control of the wrist. Journal of NeuroEngineering and Rehabilitation 6:29.
- Schouten AC, Mugge W, Van der Helm FCT (2008) NMClab, a model to assess the contributions of muscle visco-elasticity and afferent feedback to joint dynamics. J Biomech 41:1659–1667.
- Schouten AC, De Vlugt E, Van Hilten JJ, Van der Helm FCT (2008) Quantifying proprioceptive reflexes during position control of the human arm. IEEE trans Biomed Eng 55:311-321.
- Stienen AHA, Schouten AC, Schuurmans J, Van der Helm FCT (2007) Analysis of reflex modulation with a biologically realistic neural network. J Comput Neurosci 23: 333-348.
- Schouten AC, De Vlugt E, Van Hilten JJ, Van der Helm FCT (2006) Design of a torque-controlled manipulator to analyse the admittance of the wrist joint. J Neurosci Meth 154:134-141.
- Van der Helm FCT, Schouten AC, De Vlugt E, Brouwn GG (2002) Identification of intrinsic and reflexive components of human arm dynamics during postural control. J Neurosci Meth 119: 1-14.
- Schouten AC, De Vlugt E, Van der Helm FCT, Brouwn GG (2001) Optimal posture control of a musculoskeletal arm model. Biol Cybern 84: 143-152.