The Department of Bionanoscience focuses on the fundamental understanding of biological processes, from the level of single molecules to the full complexity of living cells. This research provides fascinating insight in the molecular mechanisms that lead to cellular function. Furthermore it enables the in vitro bottom-up construction of cellular machinery and it impacts applications ranging from biomolecular diagnostics to novel antibiotics and targeted nanomedicine. The department features a strongly multidisciplinary and international team of scientists, whose research areas include single-molecule biophysics, synthetic biology, as well as (quantitative) cell biology.
14 April 2023
TU Delft researchers shed new light on the motor of DNA replication
DNA replication is the process whereby cells make an exact copy of their DNA before cell division. A key part of the intricate DNA replication machinery is a molecular motor called CMG, which has the vital task of separating the two strands of the DNA double helix so that they can be copied. An interdisciplinary team of researchers from TU Delft has now developed a new methodology to assemble and image the motion of CMG with unprecedented resolution.
15 March 2023
Stan Brouns appointed as professor
The Executive Board has appointed Stan Brouns as full professor of Molecular Microbiology at the department of Bionanoscience as of 7 February 2023. His work focuses on how microbes defend themselves from viruses. Brouns: “Bacteria have had a few billion years of evolution to come up with all sorts of clever ways to defend themselves from viruses. We aim to uncover what they have evolved over all this time.”