There are open positions for BSc and MSc students with backgrounds ranging from microbiology to physics. If you are looking for a PhD or post-doctoral position, please contact Liedewij to explore possibilities.
Possible research directions are:
- Studying reproducibility and reversibility of evolutionary trajectories by combining experimental evolution in budding yeast, whole genome sequencing and modelling.
- Using fluorescence microscopy to unravel biophysical and biochemical changes underlying adaptation of the yeast polarization machinery to a strong genetic perturbation.
- Establishing a minimal in vitro system to study the dynamics and adaptability of a GTPase network.
- Ideas for other projects in the line of the lab's interest are welcomed as well.
- Master Project: Epigenetic dosage adaptation as a force of evolution
- Investigating protein domains as the building blocks of the yeast polarity network
- Establishing a framework of concepts and mechanisms in intracellular organisation
- Exploring how polarity proteins shake hands – with whom, when, how fast, and how long?
- Multivalent interactions in a DNA-colloidal system
- Construction of multivalent proteins via DNA nanostars