The Department of Bionanoscience focuses on the fundamental understanding of biological processes, from the level of single molecules to the full complexity of living cells. This research provides fascinating insight in the molecular mechanisms that lead to cellular function. Furthermore it enables the in vitro bottom-up construction of cellular machinery and it impacts applications ranging from biomolecular diagnostics to novel antibiotics and targeted nanomedicine. The department features a strongly multidisciplinary and international team of scientists, whose research areas include single-molecule biophysics, synthetic biology, as well as (quantitative) cell biology.
23 February 2022
Signal discovered that connects cell size with cell growth
The mechanisms connecting growth with cell size have been mysterious – up till now: in a recent publication in Current Biology, researchers from TU Delft and AMOLF have uncovered that the signaling molecule ppGpp is essential to regulate cell size. Surprisingly, they also discover cells adjust their sizes to concentrations of ppGpp, rather than strictly according to growth rate.
07 February 2022
ERC Proof of Concept Grant for Arjen Jakobi
Arjen Jakobi (Department of Bionanoscience) receives the ERC Proof of Concept Grant for his groundbreaking research on cryogenic electron microscopy (cryo-EM). "This grant will allow us to take our new CryoChip technique for high resolution images of protein molecules to the next level for the development of new drugs," says Jakobi.