The Ottens Lab focuses on the following research fields:

  • Micro bio systems technology and micro fluidics
  • Bioprocess equipment miniaturization,
  • General phase behavior of biomaterials, including crystallization and precipitation,
  • Protein separation, purification and characterization,
  • Fast conceptual bio(pharma)process design (HTPD), and bioprocess integration,
  • Process chromatography of biologicals and nutraceuticals,
  • Continuous bioprocessing (e.g. Simulated Moving Bed technology), 
  • Transport phenomena and bioseparation science.

Current projects


Dr Marcel Ottens, PDEng

Associate Professor

State of the art services

We provide professional services on high-throughput screening (HTS), purification process development and characterization.

Hybrid HTPD Explained

Interview Marcel Ottens on HTPD at the BioProcess International Conference, Prague, CZ, 2014

Extended Video Abstract of Nfor, et al, Multi-Dimensional Fractionation and Characterization of Crude Protein Mixtures: Toward Establishment of a Database of Protein Purification Process Development Parameters, Biotechnology & Bioengineering, 109(12), 2012 

Chip Technology

On-chip chromatography and particle & cell handling. Hoon, et all, Programmable v-type valve for cell and particle manipulation in microfluidic devices, Lab Chip, 2016, 16, 305-311, DOI: 10.1039/C5LC01206F

Deshpande, et all, Biofunctionalization and self-interaction chromatography in PDMS microchannels, Biochemical Engineering Journal, 67, 111-119, 2012

Häusler, et all, Microfluidic diffusion coefficient measurements: The optimal H-cell, Chemical Engineering Science, 72, 45-50, 2012