One Million Euro for studies of an early recognition of an aneurysm (TU Delft, Leiden UMC, Maastricht UMC+)


At present, an existence of a pathological enlargement of the largest blood vessel (aorta), so-called aneurysm, is usually discovered when is already too late for the patients. In a majority of cases, the aneurysm is detected only after rupturing, with disastrous consequences. Due to very intensive internal bleeding, mortality rates are very high. Even for patients reaching a hospital, the chance of survival is just around 60%. It is estimated that more than 300 000 persons in the Netherlands are at risk of developing an aneurysm.


The ultimate goal of Researchers from the Delft University of Technology (lead by Dr. Sasa Kenjeres TNW/ChemE), University Medical Centers in Leiden (Prof. Hildo Lamb MD, Dr. J. J.M. Westenberg, Radiology Department and Dr. Arthur Scholte MD, Cardiology Department) and Maastricht (Dr. Simon Schalla MD and Dr. Bouke Adriaans MD, Cardiology Department) is to change the current practice. From the Dutch Heart Foundation (Hartstichting), their project proposal called RADAR (Earlier Recognition of Aortic Dissection and Aneurysm Rupture) received one million Euro to develop new methods for an earlier detection of an aneurysm. 


This will be achieved by combing the state-of-art MRI measurements (LUMC and Maastricht UMC+) and advanced computational fluid dynamics (CFD) models for the blood flow in the patient-specific anatomically realistic geometries (TU Delft). Based on this integrated approach,  new risk factors associated with the probability of an aneurysm rupture will be proposed. This will make it possible to have a more accurate earlier detection of an aneurysm and will provide more effective treatments with a significantly reduced mortality.


For any questions concerning this project, please contact Sasa Kenjeres