Life Sciences projects

Below is an overview of the current BSc and MSc student projects. Looking for something specific? Please feel free to contact one of the below researchers directly to discuss the possibilities.


We address neuroscience questions through functional imaging. We develop tools with roots in physics, biochemistry, optics, mathematics and nanofabrication and we're interested in how brain cells work on every level, from biophysical principles to consequences in behavior and from subcellular compartments to complete organisms. Our lab is in its startup phase and we will have exciting projects that offer one or a combination of the following activities: Optical engineering, mechanical engineering, genetic engineering, nano-engineering; programming; cell culturing and imaging. 

Light and electron microscopy

We use light and electron microscopy to study how the brain develops.  Our goal is to develop tools to image synapse function and structure in living zebrafish embryos, and connect this to nanoscale maps made using correlative photon and electron techniques.

Integrated Microscopy (photon and electron technology)

All microscopes have limitations, which hinders us in studying materials and understanding diseases. We try to push these limitations with Integrated Microscopy: new instruments and techniques based on physically integrating photon and electron technology. Our aim is to develop higher resolution, higher content, and higher throughput microscopy techniques and show their application in relevant biomedical and nanophotonic scientific research.

Jacob Hoogenboom

Optical tomographic techniques

Optical tomographic techniques are applied in various areas ranging from hospitals to manufacturing facilities. In my team we develop novel optical tomographic techniques for imaging and sensing. We do this by modeling the physical imaging/sensing process using computational techniques, apply it for image construction or quantitative sensing, and implement it in hardware in the lab. If you like the combination of signal processing, computer simulations and experimental work combined in a single project than optical tomography may just be something for you.

Computational Microscopy

Our field of work is Computational Microscopy; this comprises the combination of imaging physics and image processing to surpass fundamental limitations imposed by physics on image formation. My main application area for this research is in life sciences at the molecular level. We have projects for students interested in programming, image processing and simulations as well as theory development in single molecule localization microscopy, but also in building microscopy setups on an optical table with adaptive optics, advanced polarization optics and liquid nitrogen cooling.