Dr. S.M. Depken
Dr. S.M. Depken
Expertise
Publications
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2022
A kinetic model predicts SpCas9 activity, improves off-target classification, and reveals the physical basis of targeting fidelity
Behrouz Eslami-Mossallam / Misha Klein / Constantijn V.D. Smagt / Koen V.D. Sanden / Stephen K. Jones / John A. Hawkins / Ilya J. Finkelstein / Martin Depken
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2022
High-throughput single-molecule experiments reveal heterogeneity, state switching, and three interconnected pause states in transcription
Richard Janissen / Behrouz Eslami-Mossallam / Irina Artsimovitch / Martin Depken / Nynke H. Dekker
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2022
Systematic decomposition of sequence determinants governing CRISPR/Cas9 specificity
Rongjie Fu / Wei He / Jinzhuang Dou / Oscar D. Villarreal / Ella Bedford / Helen Wang / Connie Hou / Liang Zhang / Martin Depken / More Authors
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2021
Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective
Mona Seifert / Subhas C. Bera / Pauline van Nies / Robert N. Kirchdoerfer / Ashleigh Shannon / Thi Tuyet Nhung Le / Xiangzhi Meng / Martin Depken / David Dulin / More Authors
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2021
The nucleotide addition cycle of the SARS-CoV-2 polymerase
Subhas Chandra Bera / Mona Seifert / Robert N. Kirchdoerfer / Pauline van Nies / Yibulayin Wubulikasimu / Salina Quack / Flávia S. Papini / Martin Depken / David Dulin / More Authors
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