Research projects

Research directions

Microtubule-based cell polarity in vitro

Building a Synthetic Cell

Finding a minimal system to establish cell polarity with microtubules

Modulating microtubules through cell-free gene expression

In vitro reconstitution and (photo)control of the microtubule plus-end tracking complex

Aster positioning

Force generation and (regulated) dynamics at microtubule ends

In vitro reconstitution of the microtubule-kinetochore coupling

Microtubule biochemistry in cell-sized volumes

Microtubule-actin interactions in vitro

Reconstitution of gradient in elongated droplets

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