Research Highlights
Laser Speckle Imaging of Flowing Blood
Van As K., Boterman J., Kleijn C. R., Kenjeres S., Bhattacharya N. (2019), “Laser Speckle Imaging of Flowing Blood: A Numerical Study”, Physical Review E, Vol. 100., 033317, pp.1-10, Editor’s Suggestion (doi: https://doi.org/10.1103/PhysRevE.100.033317)
Photo: TomoPIV setup of the left ventricle
Source: H. Saaid, J. Voorneveld, C. Schinkel, J. Westenberg, F. Gijsen, P. Segers, P. Verdonck, N. de Jong, J. G. Bosch, S. Kenjeres, T. Claessens (2019), "Tomographic PIV in a model of the left ventricle: 3D flow past biological and mechanical heart valves",Journal of Biomechanics 90, pp.40-49 (doi: https://doi.org/10.1016/j.jbiomech.2019.04.024)
Animation: 4D CFD simulations of Blood Flow in Left Ventricle with moving Mitral Valve
Source: Khalafvand S. S., Xu F., Westenberg J., Gijsen F., Kenjeres S. (2019), “Intraventricular blood flow with a fully dynamic mitral valve model”, Computers in Biology and Medicine, Vol. 104, pp.197-204 (doi: 10.1016/j.compbiomed.2018.11.024)
Invited Review Paper
Source: Kenjeres S. (2018), “On modeling and eddy-resolving simulations of flow, turbulence, mixing and heat transfer of electrically conducting and magnetizing fluids: A review”, Int. J. Heat and Fluid Flow, Vol.73, pp.270-297 (doi: 10.1016/j.ijheatfluidflow.2018.09.003)
Animation: Time-Resolved Particle Image Velocimetry (TR-PIV) measurements of Flow in Left Ventricle
Source: Khalafvand S. S., Voorneveld J. D., Muralidharan A., Gijsen F. J. H., Bosch J. G., van Walsum T., Haak A., de Jong N., Kenjeres S. (2018), “Assessment of human left ventricle flow using statistical shape modelling and computational fluid dynamics”, Journal of Biomechanics 74, pp.116-125 (doi: 10.1016/j.jbiomech.2018.04.030)
Click to animate: optical (oPIV) and ultrasound (ePIV) PIV of the instantaneous velocity field in model of left ventricle (courtesy of Erasmus Medical Center Rotterdam and Kenjeres Lab)
Source: Voorneveld J., Muralidharan A., Hope T., Vos H. J., Kruizinga P., van der Steen A. F. W., Gijsen F. J. H., Kenjeres S., de Jong N. and Bosch J. G. (2018) “High frame rate ultrasound particle image velocimetry for estimation of high velocity left ventricular flow patterns”, IEEE Transaction on Ultrasonics, Ferroelectrics, and Frequency Control, Vol. 65, Issue 12, pp.2222-2232 (doi: 10.1109/TUFFC.2017.2786340)
Figure: flow patterns in the patient-specific upper and central airways (Large Eddy Simulation results)
Source: Kenjeres S. and Tjin J. L. (2017), “Numerical Simulations of Targeted Delivery of Magnetic Drug Aerosols in the Human Upper and Central Respiratory System: A Validation Study”, Royal Society Open Science, Vol.4 (12), Art.No. 170873, pp.1-24 (doi: 10.1098/rsos.170873)
Figure: Contours of the local deposition efficiency of the medical drug within the patient-specific lung geometry: (a) passive; (b) active (Magnetic Drug Targeting)
Source: Kenjeres S. (2016), “On Recent Progress in Modelling and Simulations of Multi-scale Transfer of Mass, Momentum and Particles in Bio-medical Applications“, Flow, Turbulence and Combustion, Vol.96 (3),pp.837-860 (doi: 10.1007/s10494-015-9669-2)
Figure: mathematical modeling and computer simulations of the initial stage of the atherosclerosis development
Source: Kenjeres S. and de Loor A. (2014), “Modeling and Simulation of Low-Density-Lipoprotein (LDL) Transport Through Multi-Layered Wall of an Anatomically Realistic Carotid Artery Bifurcation”, Journal of the Royal Society Interface, Vol.11 (91), Art. No. 2013094, pp. 1- 13 (doi: 10.1098/rsif.2013.0941)