The Department of Bionanoscience focuses on the fundamental understanding of biological processes, from the level of single molecules to the full complexity of living cells. This research provides fascinating insight in the molecular mechanisms that lead to cellular function. Furthermore it enables the in vitro bottom-up construction of cellular machinery and it impacts applications ranging from biomolecular diagnostics to novel antibiotics and targeted nanomedicine. The department features a strongly multidisciplinary and international team of scientists, whose research areas include single-molecule biophysics, synthetic biology, as well as (quantitative) cell biology.
14 April 2021
Chirlmin Joo receives VICI grant for identifying proteins one at a time
Researcher Chirlmin Joo of TU Delft will receive a VICI grant for developing a method to sequence proteins one at a time. He will receive 1.5 million euros from the Netherlands Organisation for Scientific Research (NWO).
26 March 2021
Researchers shed new light on DNA replication
In preparation for cell division, cells need to copy (‘replicate’) the DNA that they contain. A team of researchers from TU Delft, collaborating with investigators from the Francis Crick Institute in London, has now shown that the protein building blocks involved in the initial steps of DNA replication are mobile but reduce their speed at specific DNA sequences on the genome. Their findings, which will be published on 26 March in the open-access journal Nature Communications, were facilitated using an integrated approach involving biophysics and biochemistry that will propel new discoveries in the field.