The Department of Bionanoscience focuses on the fundamental understanding of biological processes, from the level of single molecules to the full complexity of living cells. This research provides fascinating insight in the molecular mechanisms that lead to cellular function. Furthermore it enables the in vitro bottom-up construction of cellular machinery and it impacts applications ranging from biomolecular diagnostics to novel antibiotics and targeted nanomedicine. The department features a strongly multidisciplinary and international team of scientists, whose research areas include single-molecule biophysics, synthetic biology, as well as (quantitative) cell biology.
14 April 2022
Rubicon grant for Jochem Vink
Jochem Vink (Bionanoscience) has received a Rubicon grant from NWO, which enables him to gain research experience at a leading institute abroad. His research will be about useful fungi attracting pathogens. He was awarded the coveted grant along with 21 other researchers who recently received their PhDs.
16 March 2022
New Cas9 model maps DNA cutting behaviour for the first time
Researchers from the TU Delft have come up with a physical-based model that establishes a quantitative framework on how gene-editing with CRISPR-Cas9 works, and allows them to predict where, with what probability, and why targeting errors (off-targets) occur. This research, which has been published in Nature Communications, gives us a first detailed physical understanding of the mechanism behind the most important gene editing platform of today.