14 April 2022
Rubicon grant for Jochem Vink
Jochem Vink (Bionanoscience) has received a Rubicon grant from NWO, which enables him to gain research experience at a leading institute abroad. His research will be about useful fungi attracting pathogens. He was awarded the coveted grant along with 21 other researchers who recently received their PhDs.
16 March 2022
New Cas9 model maps DNA cutting behaviour for the first time
Researchers from the TU Delft have come up with a physical-based model that establishes a quantitative framework on how gene-editing with CRISPR-Cas9 works, and allows them to predict where, with what probability, and why targeting errors (off-targets) occur. This research, which has been published in Nature Communications, gives us a first detailed physical understanding of the mechanism behind the most important gene editing platform of today.
23 February 2022
Signal discovered that connects cell size with cell growth
The mechanisms connecting growth with cell size have been mysterious – up till now: in a recent publication in Current Biology, researchers from TU Delft and AMOLF have uncovered that the signaling molecule ppGpp is essential to regulate cell size. Surprisingly, they also discover cells adjust their sizes to concentrations of ppGpp, rather than strictly according to growth rate.
07 February 2022
ERC Proof of Concept Grant for Arjen Jakobi
Arjen Jakobi (Department of Bionanoscience) receives the ERC Proof of Concept Grant for his groundbreaking research on cryogenic electron microscopy (cryo-EM). "This grant will allow us to take our new CryoChip technique for high resolution images of protein molecules to the next level for the development of new drugs," says Jakobi.
31 January 2022
The Boukany and the Koenderink groups have been awarded an EMW-M-2 grant (700 kEuro)
Genome editing technologies such as CRISPR-Cas systems are revolutionizing the life sciences because they make it possible to change or repair the genomes of cells with high precision. However, a major challenge that hampers widespread application is that genome editing requires getting molecular tools (nucleic acids and enzymes) into the cell, across the its insulating membrane.
11 January 2022
ERC Starting Grant for four TU Delft researchers
The European Research Council (ERC) has announced the ERC Starting Grants for young researchers. Four of them are scientists from TU Delft. This European grant of €1.5 million for a five-year programme is intended to enable individual scientists to build their own teams and conduct groundbreaking research.
04 November 2021
Scanning a single protein, one amino acid at a time
Using nanopore DNA sequencing technology, researchers from TU Delft and the University of Illinois have managed to scan a single protein: by slowly moving a linearized protein through a tiny nanopore, one amino acid at the time, the researchers were able to read off electric currents that relate to the information content of the protein. The researchers published their proof-of-concept in Science today. The new single-molecule peptide reader marks a breakthrough in protein identification, and opens the way towards single-molecule protein sequencing and cataloguing the proteins inside a single cell.
02 November 2021
Marileen Dogterom elected as KNAW president
We warmly congratulate professor Marileen Dogterom on her appointment as the president of the Royal Netherlands Academy of Arts and Sciences (KNAW), the forum, conscience, and voice of the arts and sciences in the Netherlands, effective June 1, 2022.
30 August 2021
Catch me if you can: a revolutionary method to study single proteins
Researchers from the technical universities of Delft and Munich have invented a new type of molecular trap that can hold a single protein in place for hours to study its natural behavior – a million times longer than before.
19 July 2021
Chirlmin Joo appointed Full Professor
The Executive Board of TU Delft has decided to appoint Chirlmin Joo (Department of Bionanoscience) as Full Professor of Single Molecule Biophysics.