Latest News

20 April 2018

Researchers build DNA replication in a model synthetic cell

Researchers build DNA replication in a model synthetic cell

Researchers at Delft University of Technology, in collaboration with colleagues at the Autonomous University of Madrid, have created an artificial DNA blueprint for the replication of DNA in a cell-like structure.

22 February 2018

Loops, loops, and more loops: This is how your DNA gets organised

Loops, loops, and more loops: This is how your DNA gets organised

Researchers from the Kavli Institute of Delft University and EMBL Heidelberg now managed for the first time to isolate and film and witnessed—in real time—how a single protein complex called condensin reels in DNA to extrude a loop.

07 February 2018

Mathematics explains why Crispr-Cas9 sometimes cuts the wrong DNA

Mathematics explains why Crispr-Cas9 sometimes cuts the wrong DNA

The discovery of the Cas9 protein has been of great value to medical science. It has simplified gene editing tremendously, and may even make it possible to eliminate many hereditary diseases in the near future. Using Cas9, researchers have the ability to cut DNA in a cell to correct mutated genes, or paste new pieces of genetic material into the newly opened spot. Initially, the Crispr-Cas9 system seemed to be extremely accurate. But unfortunately, it is now apparent that Cas9 sometimes also cuts other DNA sequences similar to the exact sequences it was programmed to target. Scientists at Delft University of Technology have developed a mathematical model that explains why Cas9 cuts some DNA sequences while leaving others alone.

01 February 2018

Clive Brown of Oxford Nanopore at Bioengineering Institute kickoff

On Tuesday 27 March, TU Delft will launch the Delft Bioengineering Institute. Main speaker is Clive Brown, Chief Technology Officer at DNA sequencing specialist Oxford Nanopore Technologies.