OPT Research Projects

Below is a brief description of the wide research activities of the section OPT. If interested in a project or for further information, please contact Dr. Iskander-Rizk or Dr. Bhattacharya.


Applications of interferometric measurements extend from measuring surfaces on the nano-scale to measuring inter-satellite distances. Our goal is to push distance measurement to its limits with present technologies.


Photoacoustics combines light and sound to achieve optical probing of materials at deeper scale than purely optical methods. When pulsed or modulated light is shone upon a material it is absorbed. The material heats up and a transient thermoelastic expansion and contraction gives way to a broadband acoustic wave. By using different optical wavelengths, different materials can be characterized and by manipulating the light and receivers different probing resolution scales can be achieved. We intend to (1) further develop photoacoustic based technology and (2) develop methodologies to extract material characteristics as a result of photoacoustic excitation. 


Developing the technology is one part of the OPt section activities. We go beyond and develop proof of concepts of the technology at the service of healthcare and industrial applications. We have collaborations with Erasmuc MC and LUMC in various projects.

Selected publications

  • 2021, Photoacoustic flow velocity imaging based on complex field decorrelation. Zangabad, R.P., Iskander-Rizk, S., van der Meulen, P., Meijlink, B., Kooiman, K., Wang, T., van der Steen, A.F. and van Soest, G. Photoacoustics, 22
  • 2019, Laser speckle imaging of flowing blood: A numerical study, K. van As, J. Boterman, C. R. Kleijn, S. Kenjeres, N. Bhattacharya,  Physical Review E, 100, 033317
  • 2019, Distance Metrology with Integrated Mode-locked Ring Laser Article, K. Hei, G. Shi, A. Hänsel, Z. Deng, S. Latkowski, S.A. van Den Berg, E. Bente, N. Bhattacharya ", IEEE Photonics , Journal DOI: 10.1109/JPHOT.2019.2940068
  • 2019, Real-time photoacoustic assessment of radiofrequency ablation lesion formation in the left atrium. Iskander-Rizk, S., Kruizinga, Beurskens, R.H., Springeling, G., Mastik, F., de Groot, N.M., Knops, P., van der Steen, A.F. and van Soest, G. Photoacoustics.
  • 2018, Catheter design optimization for practical intravascular photoacoustic imaging (IVPA) of vulnerable plaques Iskander-Rizk, S., Wu, M., Springeling, G., Mastik, F., Beurskens, R. H., van der Steen, A. F., & van Soest, G. In Diagnostic and Therapeutic Applications of Light in Cardiology 2018 (Vol. 10471, pp. 29-36). SPIE.
  • 2018. Photoacoustic-Enabled RF Ablation Catheters for Lesion Monitoring. Iskander-Rizk, S., Springeling, G., Kruizinga, P., Beurskens, R.H., van der Steen, A.F. and van Soest, G. 2018 IEEE International Ultrasonics Symposium (IUS) (pp. 1-4). IEEE
  • 2017, Temperature measurement using frequency comb absorption spectroscopy of CO2, A. Hänsel, A. Reyes-Reyes, S. Persijn, H. P. Urbach, N. Bhattacharya ", Review of Scientific Instruments, 88, 053113