Research Interest: Quantitative super-resolution microscopy on DNA replication proteins in human cells
After studying Medical Natural Sciences at the Vrije Universiteit in Amsterdam, she got interested in the ability to visualize the activity and dynamics of single proteins within protein complexes. As such, she did her PhD on single-molecule fluorescence studies on T7 DNA bacteriophage replication proteins, starting in 2010 at the Harvard Medical School, Boston, USA and finishing in 2014 at the Rijksuniversiteit of Groningen, the Netherlands. Afterwards, she wanted to push her knowledge and experimental toolset by investigating, on the one hand, more complex model organisms, i.e. eukaryotic cells, and, on the other hand, by increasing the resolving power of her technique by using super-resolution microscopy. As such, she did her Postdoc at the Freie Universitaet Berlin, Germany, on the application and improvement of the super-resolution technique DNA-PAINT to observe various structures in the nucleus of the eukaryotic cell.