Prof.dr. L.F.A. Wessels

vakken
2006 - Advanced Bioinformatics (D)
2007 - Advanced Bioinformatics (D)
2008 - Advanced Bioinformatics (D)
2009 - Advanced Bioinformatics (D)
publicaties
Targeting the RB-E2F pathway in breast cancer

peer reviewed : Y

Oncogene: including Oncogene Reviews (2016) 7 pagina's , p. 4829-4835

auteurs

  • J. Johnson
  • B. Thijsen
  • U McDermott
  • M. Garnett
  • Lodewyk Wessels
  • R Bernards
Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition

peer reviewed : Y

OncoTarget (2016) 13 pagina's , p. 69816-69828

auteurs

  • Martijn A.J. Koppens
  • Gergana Bounova
  • Paulien Cornelissen-Steijger
  • Nienke de Vries
  • Owen J. Sansom
  • Lodewyk Wessels
  • Maarten van Lohuizen
A Landscape of Pharmacogenomic Interactions in Cancer

peer reviewed : Y

Cell (2016) 15 pagina's , p. 740-754

auteurs

  • Francesco Iorio
  • Theo A. Knijnenburg
  • Daniel J. Vis
  • Graham R. Bignell
  • Michael P. Menden
  • Michael Schubert
  • Nanne Aben
  • Emanuel Gonçalves
  • Syd Barthorpe
  • Lodewyk Wessels
  • More Authors
A novel independence test for somatic alterations in cancer shows that biology drives mutual exclusivity but chance explains most co-occurrence

peer reviewed : Y

Genome Biology (Online) (2016) 17 pagina's , p. 1-17

auteurs

  • Sander Canisius
  • Lodewyk Wessels
  • John W. M. Martens
BMC

peer reviewed : Y

BMC Systems Biology (2016) 8 pagina's , p. 1-8

auteurs

  • Bram Thijssen
  • Tjeerd M.H. Dijkstra
  • Tom Heskes
  • Lodewyk Wessels
Computational pan-genomics

peer reviewed : Y

Briefings in Bioinformatics (2016) 18 pagina's , p. 1-18

auteurs

  • Tobias Marschall
  • Manja Marz
  • TEPMF Abeel
  • Louis Dijkstra
  • Bas E. Dutilh
  • Ali Ghaffaari
  • Paul Kersey
  • Wigard P. Kloosterman
  • Jeroen de Ridder
  • Lodewyk Wessels
  • More Authors
Defining chromosomal translocation risks in cancer

peer reviewed : Y

Proceedings of the National Academy of Sciences of the United States of America (2016) 8 pagina's , p. E3649-E3656

auteurs

  • Marc A. Hogenbrink
  • Marinus R. Heideman
  • Iris de Rink
  • Arno Velds
  • Ron M. Kerkhoven
  • Lodewyk Wessels
  • Heinz Jacobs
Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells

peer reviewed : Y

Gastroenterology (2016) 14 pagina's , p. 684-697

auteurs

  • Martijn A.J. Koppens
  • Gergana Bounova
  • Gaetano Gargiulo
  • Ellen Tanger
  • Hans Janssen
  • Paulien Cornelissen-Steijger
  • Marleen Blom
  • Ji-Ying Song
  • Lodewyk Wessels
  • Maarten van Lohuizen
Integration of genomic, transcriptomic and proteomic data identifies two biologically distinct subtypes of invasive lobular breast cancer

peer reviewed : Y

Scientific Reports (2016) 13 pagina's , p. 1-13

auteurs

  • M Michaut
  • SF Chin
  • I Majewski
  • TM Severson
  • T Bismeijer
  • L de Koning
  • JK Peeters
  • PC Schouten
  • OM Rueda
  • AJ Bosma
  • LFA Wessels
  • More Authors
Logic models to predict continuous outputs based on binary inputs with an application to personalized cancer therapy

peer reviewed : Y

Scientific Reports (2016) 14 pagina's , p. 1-14

auteurs

  • Theo A. Knijnenburg
  • Gunnar W Klau
  • Francesco Lorio
  • Mathew J. Garnett
  • Ultan McDermott
  • I Shmulevich
  • Lodewyk Wessels