Prof.dr.ir. M.J.T. Reinders

profiel

Resume

Prof Reinders holds a position at the Delft University of Technology as well as at the Leiden University Medical Center. In Delft he heads the Pattern Recognition and Bioinformatics section in one of the Computer Science departments of the Faculty of Electtrical Engineering, Mathematics and Computer Science. The section consists of three research labs: Delft Bioinformatics Lab (5 staff); Pattern Recognition Lab (2 staff); Computer Vision Lab (3 staff) and includes a group of ~60 people (incl. ~10 scientific staff members (HL/UHD/UD’s), ~30 PHDs/Postdocs, ~20MSCs).  In Leiden he heads the Leiden Computational Biology Center.  This center generates new biological insights with clinical applicabilities using computational tools to analyse molecular data. The groupconsists of ~15 people (incl. 3 scientific staff memberts (tenure trackers), ~12PDs/MScs).

Research description

Prof Reinders group in Delft is recognized as international experts on machine learning and in his bioinformatics research he applies the cutting-edge machine learning expertise to develop data-driven analysis methodologies to gain molecular biology insights. His group in Leiden uses computational biology to progress clinical applicability of molecular data with a focus on newest technologies, such as single cell or spatio-temporal omics data. He initiated work on molecular classification and genetic network modelling, and has a strong track record on next-generation sequencing analysis, network-based analysis, as well as integration of genomic data.

google sholar:    scholar.google.com/citations?user=h52_bg0AAAAJ
url prb:               www.prb.tudelft.nl
url lcbc:              www.lcbc.nl

Educational activities

- Coordinator of “Master track Bioinformatics” within the Computer Science program
- Supervised ~100 master students
- Lecturer of 7 graduate courses (currently 1), “Functional Genomics and Systems Biology”
- Lecturer of 10 undergraduate courses (currently 3), ao “Datamining” and “Bioinformatics” 
- Lecturer of 7 postgraduate courses (currently 1), “NBIC course on Pattern Recognition”

Professional memberships

From 2017       Member scientific advisory board Informatics Platform Netherlands
From 2014       Member scientific advisory board Dutch Techcentre for Life Science
From 2013       Visiting professor at Clinical Genetics, Free University Medical Centre
From 2011       Director of the TUD-EEMCS Graduate School
2010-2017       Scientific Director of the Netherlands Bioinformatics Center (NBIC)
From 2009       Heading the Pattern Recognition and Bioinformatics Section (PRB), Computer 2005-2015       Chair of the TUD-EEMCS Scientific Advisory Board (VCWB)

publicaties
Bioinformatics in the Netherlands

peer reviewed : Y

Briefings in Bioinformatics (2017) 9 pagina's , p. 1-9

auteurs

  • Celia W.G. van Gelder
  • Rob W.W. Hooft
  • Merlijn N. van Rijswijk
  • Linda van den Berg
  • Ruben G. Kok
  • Marcel Reinders
  • Barend Mons
  • Jaap Heringa
Brain transcriptome atlases

peer reviewed : Y

Brain Structure and Function (2017) 24 pagina's , p. 1557-1580

auteurs

  • Ahmed Mahfouz
  • Sjoerd M.H. Huisman
  • Boudewijn P.F. Lelieveldt
  • Marcel J.T. Reinders
BrainScope

peer reviewed : Y

Nucleic Acids Research (2017)

auteurs

  • Sjoerd M.H. Huisman
  • Baldur Van Lew
  • Ahmed Mahfouz
  • Nicola Pezzotti
  • Thomas Höllt
  • Lieke Michielsen
  • Anna Vilanova
  • Marcel J.T. Reinders
  • Boudewijn P.F. Lelieveldt
Characterization of pathogenic SORL1 genetic variants for association with Alzheimer's disease

peer reviewed : Y

European Journal of Human Genetics (2017) 9 pagina's , p. 973-981

auteurs

  • Henne Holstege
  • Sven J. van Der Lee
  • Marc Hulsman
  • Tsz Hang Wong
  • Jeroen G.J. van Rooij
  • Marjan Weiss
  • Eva Louwersheimer
  • Frank J, Wolters
  • Najaf Amin
  • Marcel J.T. Reinders
  • More Authors
Co-expression Patterns between <i>ATN1</i> and <i>ATXN2</i> Coincide with Brain Regions Affected in Huntington’s Disease

peer reviewed : Y

Frontiers in Molecular Neuroscience (2017) 13 pagina's , p. 1-13

auteurs

  • Arlin Keo
  • N. Ahmad Aziz
  • Oleh Dzyubachyk
  • Jeroen Van Der Grond
  • Willeke M.C. van Roon-Mom
  • Boudewijn P.F. Lelieveldt
  • Marcel J.T. Reinders
  • Ahmed Mahfouz
Comparing methods for fetal fraction determination and quality control of NIPT samples

peer reviewed : Y

Prenatal Diagnosis (2017) 5 pagina's , p. 769-773

auteurs

  • Daphne M van Beek
  • Roy Straver
  • Marian M. Weiss
  • Elles M.J. Boon
  • Karin Huijsdens-van Amsterdam
  • Cees B.M. Oudejans
  • Marcel J.T. Reinders
  • Erik A. Sistermans
Continuous infusion of manganese improves contrast and reduces side effects in manganese-enhanced magnetic resonance imaging studies

peer reviewed : Y

NeuroImage (2017) 9 pagina's , p. 1-9

auteurs

  • Dana S. Poole
  • Nathalie Doorenweerd
  • Jaap J. Plomp
  • Ahmed Mahfouz
  • Marcel Reinders
  • Louise van der Weerd
Cortical Spreading Depression Causes Unique Dysregulation of Inflammatory Pathways in a Transgenic Mouse Model of Migraine

peer reviewed : Y

Molecular Neurobiology (2017) 11 pagina's , p. 2986-2996

auteurs

  • Else Eising
  • Reinald Shyti
  • Peter A.C. 't Hoen
  • Lisanne S. Vijfhuizen
  • Sjoerd M.H. Huisman
  • Ludo A. M. Broos
  • Ahmed Mahfouz
  • Marcel J.T. Reinders
  • Michel D. Ferrari
  • Else A. Tolner
  • Boukje de Vries
  • Arn M.J.M. van den Maagdenberg
Mining for osteogenic surface topographies

peer reviewed : Y

Biomaterials (2017) 12 pagina's , p. 49-60

auteurs

  • Frits F.B. Hulshof
  • Bernke J. Papenburg
  • Aliaksei Vasilevich
  • Marc Hulsman
  • Yiping Zhao
  • Marloes Levers
  • Natalie Fekete
  • Meint de Boer
  • Huipin Yuan
  • Marcel Reinders
  • More Authors
Timing and localization of human dystrophin isoform expression provide insights into the cognitive phenotype of Duchenne muscular dystrophy

peer reviewed : Y

Scientific Reports (2017) 12 pagina's , p. 1-12

auteurs

  • Nathalie Doorenweerd
  • Ahmed Mahfouz
  • Maaike van Putten
  • Rajaram Kaliyaperumal
  • Peter A.C. 't Hoen
  • Jos G.M. Hendriksen
  • Annemieke M. Aartsma-Rus
  • Jan J.G.M. Verschuuren
  • Erik H. Niks
  • Marcel J.T. Reinders
  • Hermien E. Kan
  • Boudewijn P.F. Lelieveldt
vakken
2006 - Functional Genomics and Systems Biology
2006 - Information Processing
2006 - Data Mining
2006 - Selected Topics in Multimedia Computing
2006 - Proteomics & Biochips
2007 - Information Processing
2007 - Selected Topics in Multimedia Computing
2007 - Functional Genomics and Systems Biology
2007 - Data Mining
2007 - Proteomics & Biochips
2009 - Information Processing
2009 - Advanced Bioinformatics
2009 - Data Mining
2007 - Specialisatie MKT 3: Project
2008 - Information Processing
2008 - Specialisatie MKT 3: Project
2008 - Functional Genomics and Systems Biology
2009 - Specialisatie MKT3: Project
2008 - Data Mining
2008 - Proteomics & Biochips
2008 - Seminar Selected Topics in Multimedia Computing
2008 - Proteomics & Biochips
2009 - Functional Genomics and Systems Biology
2009 - Seminar Selected Topics in Multimedia Computing
2009 - Genome Scale Data Analysis
2009 - Advanced Bioinformatics (D)
2010 - Specialisatie MKT3: Project
2010 - Genome Scale Data Analysis
2010 - Data Mining
2009 - Signal Processing and Control
2010 - Seminar Selected Topics in Multimedia Computing
2010 - Functional Genomics and Systems Biology
2010 - Signal Processing and Control
2012 - Genome Scale Data Analysis
2011 - Data Mining
2011 - Advanced Bioinformatics
2011 - Seminar Selected Topics in Multimedia Computing
2011 - Functional Genomics and Systems Biology
2011 - Final Project
2011 - Information & Knowledge Engineering project
2011 - Genome Scale Data Analysis
2014 - Genome Scale Data Analysis
2013 - Bioinformatica
2013 - Bioinformatica
2014 - Bioinformatica
2014 - Final Project
2014 - Functional Genomics and Systems Biology
2014 - Advanced Bioinformatics
2012 - Functional Genomics and Systems Biology
2012 - Advanced Bioinformatics
2012 - Seminar Selected Topics in Multimedia Computing
2012 - Final Project
2012 - Information & Knowledge Engineering project
2012 - Data Mining
2013 - Final Project
2013 - Genome Scale Data Analysis
2014 - Introduction to Life Science
2013 - Functional Genomics and Systems Biology
2013 - Advanced Bioinformatics
2016 - Bio-informatica
2017 - Datamining
2016 - Datamining
2016 - Bioinformatica
2017 - Bio-informatica
2015 - Final Project
2015 - Functional Genomics and Systems Biology
2015 - Introduction to Life Science
2015 - Bio-informatica
2017 - Bio-informatica
2017 - Bioinformatica
2016 - Bio-informatica
2017 - Datamining
2015 - Datamining
2015 - Datamining
2015 - Bioinformatica
2017 - Functional Genomics and Systems Biology
2017 - Introduction to Life Science
2016 - Datamining
2016 - Introduction to Life Science
2016 - Functional Genomics and Systems Biology
nevenwerkzaamheden
-Adviseur/Consultant - VU Medisch Centrum

2016-01-01 - 2018-01-01

Onderwijs