ImPhys colloquium | Chris Xu

Chris Xu School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853, USA

Title: Pushing the limits of multiphoton imaging in living systems

Abstract:

Multiphoton microscopy is an indispensible tool for high-resolution, non-invasive imaging of structure and function deep within intact tissues and organs. In this talk, we will focus on technology development for imaging deep, wide and fast. We will review the state-of-the-art multiphoton microscopes for in vivo imaging of living tissues and animal models, and describe a number of directions for continued development, including new laser sources, new spectral windows and optimum illumination schemes. We will further discuss the limits of the imaging depth, volume, and speed in multiphoton imaging of living systems.

Biographic Sketch

Chris Xu is the IBM Chair Professor of Engineering at Cornell University. He is the Director of the School of Applied and Engineering Physics and the Mong Family Foundation co-director of Cornell Neurotech. His current research areas are multiphoton microscopy for deep tissue imaging, multiphoton microendoscopy for clinical applications, and fiber-based devices and systems for optical imaging. Prior to Cornell, he was a member of technical staff at Bell Laboratories and pioneered breakthrough development of fiber optic communication systems based on differential phase-shift keying. He received his Ph.D. in Applied Physics from Cornell University and his B.S. in Physics from Fudan University. He has won the NSF CAREER award, Bell Labs team research award, the Tau Beta Pi Professor of the Year Award, and two teaching excellence awards from Cornell Engineering College. He received the 2017 Cornell Engineering Research Excellence Award. He is a fellow of the Optica and a fellow of the National Academy of Inventors.