Student projects

MEP - Development of a tool for the prediction of protein diffusion coefficient using a QSPR model 

Start date: Open now 

Supervisor: Tim Neijenhuis & Tiago Da Silva 

Protein diffusion coefficients are important parameters for the design and analysis of separation and purification processes. This important parameter has been demonstrated to mainly depend on different phenomena, which range from the protein’s properties (e.g. molecular weight) to environmental conditions (pH, buffer composition, protein concentration, among others). This project is composed of two main research targets: i) determination of protein diffusion coefficients with the in-house microfluidics chip of different proteins under different conditions, ii) train and validate the QSPR model to predict the diffusion coefficient of different proteins. More information: Project description


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