Bioengineering Principal Investigators


Below you can find profiles of TU Delft Principal Investigators who work on engineering solutions in, with and for biology and are looking for collaboration.

PDF Delft Bioengineering Institute PIs

BioDay/BioDate Organization Committee

Caroline Paul

Biocatalysis and organic chemistry expert looking for materials, bioinformatics, structural biology and more.  

Angelo Accardo

3D microfabrication, mechanical characterization and biomaterials expert looking for 3D Immunofluorescence Imaging, cell biologists and polymer/hydrogel chemists. 

 

 

Martin Depken

Theoretical Biophysicist looking for bioinformatics.

Dimitra Dodou

Adhesion, soft-tissue grip and experimental methods expert looking for soft polymers, stimuli-responsive polymers, soft matter and soft robotics experts. 

 

 

Joana Goncalves

Computational Biologist looking for single cell time series, gene editing and molecular pertubation data.

 

 

Ralph Lindeboom

Biogeotechnologist looking for thermochemical biomass processing, optics experts and environmental microbiologists.  

Dimphna Meijer

Neuroscientist looking for protein chemists, electrical nanocircuits and in vivo imaging. 

All TU Delft Bioengineering PIs

Dimitra Dodou

Adhesion, soft-tissue grip and experimental methods expert looking for soft polymers, stimuli-responsive polymers, soft matter and soft robotics experts. 

 

 

Amir Zadpoor

3D/4D printing, biofabrication and metamaterials expert looking for microbiology, embedded printable electronics and big data. 

 

 

Jie Zhou

Materials scientist looking for experts in cyto-, histo-, and hemocompatibility tests. 

 

 

Raf van de Plas

Molecular imaging and computational mass spectrometry expert looking for molecular imaging applications and problems in big data imaging analysis and analytical chemistry. 

 

 

Carlas Smith

Super-resolution microscopy expert looking for bio-applications for super-resolution microscopy, single-molecule imaging and biophysics. 

 

 

Michel Verhaegen

Numerics for Control and Identification (N4CI) expert looking for large scale network identification and control problems, and high resolution imaging applications with BioData. 

 

 

Jovana Jovanova

Bio-inspired design expert looking for marine biologists, soft robotics and 4D printing.

Angelo Accardo

3D microfabrication, mechanical characterization and biomaterials expert looking for 3D Immunofluorescence Imaging, cell biologists and polymer/hydrogel chemists. 

 

 

Ivan Buijnsters

Materials & Surfaces Engineer looking for biochemists, water/wastewater engineers and surface chemists.

 

 

Sabina Caneva

Nanotechnology, 2D materials and nanopore expert looking for synthetic biology, biochemistry and single molecule imaging. 

 

 

Murali Ghatkesar

Micro-Nano Engineer looking for single cell biologists, biophysicists and biochemists. 

 

 

Hassan HosseinNia

Advanced motion control, soft actuator and distributed actuator expert looking for precision robotics and abdominal assist device. 

 

 

Burak Eral

Soft matter, crystals and microfluidics guy looking for human cell line culturing know-how, biomineralization and gut bacteria. 

 

 

Wiebren de Jong

Thermochemical biomass conversion, biorefinery and energy storage systems expert looking for process system integration, biorefinery and energy storage.  

 

 

Daniel Tam

(Bio-)fluid dynamicist looking for algae-based bio-process technology, microfabrication for microfluidics (electro-osmosis) and cell biology. 

 

 

Anne-Catherine Dieudonné

Geomechanics expert looking for environmental microbiology, microfluidics and imaging techniques.

 

 

Julia Gebert

Soil microbiologist looking for microbiology, population analysis (DNA/RNA profiling) and water chemistry.

Doris van Halem

Drinking water treatment expert looking for engineering microbial communities, antibiotic resistance in water treatment and biofilm characterization. 

 

 

Merle de Kreuk

Wastewater treatment expert looking for enzymes (activity), microbiology (bio-informatics) and computational fluid dynamics (CFD).

 

 

Jules van Lier

(Waste)water treatment expert looking for microbial functionality in complex systems. 

 

 

Ralph Lindeboom

Biogeotechnologist looking for thermochemical biomass processing, optics experts and environmental microbiologists.  

Marie-claire ten Veldhuis

Hydrometeorologist looking for in-vivo imaging, microfluidics and in-vivo measurement of water potential and pressure dynamics. 

 

 

Thomas Abeel

Microbial genomics and bioinformatics expert looking for metagenomics and microbial genomics projects. 

 

 

Joana Goncalves

Computational Biologist looking for single cell time series, gene editing and molecular pertubation data.

 

 

Marcel Reinders

Bioinformatics, computational biology and machine learning expert looking for single cell biology, long-read sequencing-based biology and molecular neuroscience. 

 

 

Tiago Costa

Microelectronics expert looking for functional imaging experts, neuroscientists and material scientists.

Borbála Hunyadi

Biomedical signal processing expert looking for open problems in bio-electrical sensor or imaging data.

 

 

Massimo Mastrangeli

Micro/nano scientist looking for complementary expertise in cell biology and tissue physiology, polymer chemistry and plasmonic/optical metamaterials.

Elvin Karana

Materials and design researcher looking for novel bio-based materials, waste-based materials and materials scientists who are interested in design collaborations.

 

 

Alexis Bohlin

Coherent Raman imaging expert looking for in-situ thermometry applications, microbial production of biofuels and microfluidics. 

 

 

Santiago Garcia

Materials scientist looking for biotechnologists to team up with.   

 

 

Stéphanie Cazaux

Planetary sciences expert looking for microbiologists, marine biologists and surface chemists.

Marie-Eve Aubin-Tam

Biophysical engineer looking for crystal formation, polymers and materials characterization.  

 

 

Greg Bokinsky

Synthetic microbiologist looking for bioinformaticists, biochemists and synthetic chemists. 

 

 

Stan Brouns

Microbiologist/Genetic Engineer looking for bioinformatics, microfabrication and microbiology. 

 

 

Christophe Danelon

Synthetic biology, minimal cell and membrane biophysics expert looking for genome editing and DNA assembly technologies. 

 

 

Cees Dekker

Biophysics, nanofabrication and nanobiology expert looking for ultralong DNA, chromatin-related proteins and divisome proteins.

 

 

Martin Depken

Theoretical Biophysicist looking for bioinformatics.

Timon Idema

Theoretical Biophysicist looking for cell biologists and experimental biophysicists. 

 

 

Arjen Jakobi

Structural Biologist looking for micro/nanofluidics, machine learning, image processing and bioinformatics.  

 

 

Chirlmin Joo

Fluorescence expert and single-molecule biophysicist looking for opportunities to collaborate. 

 

 

Gijsje Koenderink

Cell and tissue biophysicist with experience in cytoskeleton and extracellular matrix mechanobiology, looking for microscopy experts, biomaterials exerts, and tissue engineers.  

 

 

Liedewij Laan

Biophysicist looking for bioinformatics and microbial ecology.

 

 

Dimphna Meijer

Neuroscientist looking for protein chemists, electrical nanocircuits and in vivo imaging. 

Kristina Djanashvili

Organic synthesis and coordination chemistry expert looking for imaging in vivo and in vitro, biological evaluation of toxicity and therapeutic effects and physical characterization of nanoparticles.

 

 

Peter-Leon Hagedoorn

Biochemist looking for spectroscopy, thermal imaging, radionuclides and metals in biology. 

 

 

Ludovic Jourdin

Microbial electrochemical technology expert looking for microbiologists, material science experts and modeling experts. 

 

 

Mark van Loosdrecht

Wastewater treatment expert looking for analysis and characterization of complex biopolymers and bioinformatics. 

 

 

Robert Mans

‘Cut, Copy, Paste, and Replace’ with DNA, engineering with evolution and bio-engines expert looking for (polymer) chemists, bio-informaticians and membrane engineers.

 

 

Duncan McMillan

Bioelectrochemist, biophysicist and molecular microbiologist looking for microbiologists, nanofabrication and surface chemists.  

 

 

Martin Pabst

Protein mass spectrometrist/microbial proteomics and glycoproteins expert looking for bioinformatics, fluorescence imaging and statistics.  

 

 

Caroline Paul

Biocatalysis and organic chemistry expert looking for materials, bioinformatics, structural biology and more.  

Aljoscha Wahl

Microbial metabolism expert looking for membrane proteins, high performance computation and single cell approaches. 

Pouyan Boukany

DNA dynamics, bio-microfluidics and cell mechanics expert looking for cell biology, surface modification and high resolution imaging. 

 

 

Rienk Eelkema

Synthetic organic, polymer chemistry and soft matter expert looking for hybrid materials (living/non-living), functionalization of biomolecules and healthcare materials.  

 

 

Valeria Garbin

Expert in stretching, breaking, and otherwise deforming soft and biological materials looking for microbiology, bioprocessing and tissue engineering.

Eduardo Mendes

Advanced soft matter expert looking for cell biologists, neuron experts and immune system experts.

 

 

Stephen Picken

Polymer materials physicist looking for biobased materials and applications. 

 

 

Luis Portela

Fluid mechanics expert looking for micro-organism models, micro-organisms genetics and dynamics of biological systems.  

 

 

Daan Brinks

Neurophysicist looking for protein evolution, biostatistics and genome editing.

Elizabeth Carroll

Opto-neuro-bio-physicist looking for experts in molecular biology, developmental biology and neuroscience. 

 

 

Jeroen Kalkman

Imaging expert fascinated by optical tomography looking for life scientists with challenging imaging problems.

David Maresca

Ultrasound imaging expert looking for protein engineering and synthetic biology.  

 

 

Sebastian Weingartner

MRI physicist looking for exciting imaging applications of functional and cellular properties.

Antonia Denkova

Radiochemist & Soft Matter Engineer looking for imaging in vitro, bioassay development and microfluidics.

 

 

Marlies Goorden

Imaging physicist looking for biological and biomedical applications for radionuclide and CT imaging.  

 

 

Zoltan Perko

Computational physicist looking for bioinformatics, radiobiology and in vivo imaging.

Albert van de Wiel

Senior consultant in internal medicine and isotope research looking for opportunities to collaborate.  

 

 


Gijsje Koenderink

About my work

We study the material properties of living cells and tissues. Living matter is unique in its ability to combine mechanical strength with active force generation and autonomous change shape. We aim to understand the physical mechanisms that underlie this striking active mechanical behavior. We combine concepts and techniques from soft matter physics, biophysics, synthetic biology, protein engineering, and mechanobiology. We furthermore develop advanced measurement techniques that combine quantitative imaging with force measurements across length scales ranging from the cell/tissue level down to molecular scales.

My main research interests

Cell biology
Mechanobiology
Active soft matter

I am looking for

Advanced microscopy
Tissue engineering
Microfluidics

My expertise and technologies to offer

Rheology
Self-assembly
Advanced microscopy

TNW
> Bionanoscience
>> Koenderink Lab for Biological Soft Matter

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Sabina Caneva

About my work

I am interested in creating nanoelectromechanical devices to study the function of mechanically-activated biological and artificial nanopores in vitro. My research combines nanofabrication, microfluidics, single-molecule conductance and fluorescence measurements. I currently work on the following research lines: (i) developing acoustic tweezers to spatially and temporally manipulate individual biomolecules in lipid bilayers using sound waves and (ii) designing and controlling dynamic DNA nanostructures.

My main research interests

Protein, DNA and solid state nanopores
Single molecule manipulation techniques (acoustic and optical tweezers)
Stimuli-responsive bionanostructures

I am looking for

Synthetic biology, biochemistry (liposomes, artificial lipid bilayers)
DNA origami nanotechnology
Super-resolution imaging 

My expertise and technologies to offer

Nanopores
2D materials
Micro/nanofabrication & microfluidics

3ME
> Precision and Microsystems Engineering (PME)
>> Dynamics of Micro and Nanosystems (DMN)

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Gijsje Koenderink

About my work

We study the material properties of living cells and tissues. Living matter is unique in its ability to combine mechanical strength with active force generation and autonomous change shape. We aim to understand the physical mechanisms that underlie this striking active mechanical behavior. We combine concepts and techniques from soft matter physics, biophysics, synthetic biology, protein engineering, and mechanobiology. We furthermore develop advanced measurement techniques that combine quantitative imaging with force measurements across length scales ranging from the cell/tissue level down to molecular scales.

My main research interests

Cell biology
Mechanobiology
Active soft matter

I am looking for

Advanced microscopy
Tissue engineering
Microfluidics

My expertise and technologies to offer

Rheology
Self-assembly
Advanced microscopy

TNW
> Bionanoscience
>> Koenderink Lab for Biological Soft Matter

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Borbála Hunyadi

About my work

I develop signal processing and machine learning solutions for biomedical problems, to unravel healthy and pathological physiology. More specifically, I discover hidden patterns in multichannel and/or multimodal datasets using both supervised (e.g. classification) and unsupervised (e.g. blind source separation) techniques. In order to tackle high-dimensional and higher order (3D+) data, I often use tensor-based techniques. I have many years of experience in epilepsy research using EEG, fMRI and wearable monitoring. I am also interested in ECG and (functional) ultrasound applications.

My main research interests

Biomedical signal processing
Brain connectivity
Clinical decision support

I am looking for

Bioelectrical sensors
(Neuro)imaging
Personalized medicine

My expertise and technologies to offer

Signal processing, in particular multi-channel
(Tensor-based) blind source separation
Pattern recognition

EWI
> Microelectronics
>> Circuit and Systems

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Tiago Costa

About my work

I develop micrometre and millimetre scale integrated circuit chips with monolithically integrated transducers for minimally invasive neuromodulation. Specifically, I am exploring miniaturized focused ultrasound devices for high spatial resolution neuromodulation of the nervous system, either non-invasively (peripheral nerves) or minimally invasively (brain). I am also interested in magnetic neuronal interfaces, and on augmenting integrated circuits chips with novel materials for biomedical applications.

My main research interests

Integrated circuits and sensors/actuators
Ultrasound neuromodulation
Magnetic neuronal stimulation and recording

I am looking for

Functional imaging experts
Neuroscientists
Material scientists

My expertise and technologies to offer

Integrated circuits
Miniaturized smart transducers
Ultrasound neuromodulation

EWI
> Microelectronics
>> Bioelectronics

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Anne-Catherine Dieudonné

About my work

My research focuses on assessing the impacts of environmental (biological, chemical, thermal, hydraulic) loads on the behaviour of geomaterials and on the performance and resilience of geotechnical structures. I aim to develop new fundamental understanding of multi-physical processes in geomaterials using state-of-the-art imaging, experimental testing and numerical modelling techniques.

My main research interests

Bio-cementation of soils
Self-healing materials
Discrete element modelling

I am looking for

Environmental microbiology
Microfluidics
Imaging techniques

My expertise and technologies to offer

Mechanical testing of geomaterials
Numerical modelling of multiphysics processes

CiTG
> Geoscience and Engineering
>> Geo-Engineering

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Sebastian Weingartner

About my work

We develop novel methods in Magnetic Resonance Imaging physics to depict previously undetectable properties on the micro-, meso- and macroscopic scale in-vivo. This spans work on signal modelling, quantitative imaging biomarkers, as well as novel imaging techniques for functional brain imaging. Most of our experiments are done on clinical MRI machines at field strengths 1.5T – 7T, enabling the direct application to human subject.

My main research interests

Magnetic Resonance Imaging
Functional neuroimaging
Imaging of cellular properties in-vivo

I am looking for

Neuroimaging
Tissue/animal models

My expertise and technologies to offer

Magnetic Resonance Imaging
In-vivo imaging
Functional neuroimaging

TNW
> Imaging Physics
>> Magnetic Resonance Systems (Mars) Lab

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Robert Mans

About my work

I develop microbial strains with optimized product formation pathways. My specific focus is on modulation of the efficiency at which microbes harvest energy from chemical conversions. I use targeted strain engineering via techniques such as CRISPR/Cas9 to replace native microbial metabolic pathways and subsequent evolutionary engineering to optimize foreign (heterologous) pathways. In the future I aim to use genetically encoded biosensors to engineer robust industrial microbial strains.

My main research interests

Membrane transporters
Bio-energetics
Biosensors

I am looking for

(Polymer) chemists
Bio-informaticians
Membrane engineers

My expertise and technologies to offer

Microbial evolution
Metabolic engineering
Quantitative bioreactor cultivation

TNW
> Biotechnology
>> Industrial Microbiology/Robert Mans Group

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David Maresca

About my work

Visualizing cellular processes occurring deep with living organisms is essential to our understanding of biology and disease. To address this challenge, we pursue fundamental advances at the interface of ultrasound imaging and molecular engineering, taking advantage of the discovery of acoustic biomolecules to interface ultrasound waves with cellular processes.

My main research interests

Biomedical ultrasound imaging
Ultrasound imaging of neural activity

I am looking for

Protein engineering
Synthetic biology

My expertise and technologies to offer

Biomolecular ultrasound imaging
Hemodynamic functional ultrasound imaging of neural activity
Genetically encoded acoustic biomolecules (also known as gas vesicles)

TNW
> Imaging Physics
>> Medical Imaging/Maresca Lab

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Julia Gebert

About my work

I investigate sediment organic matter and the role of biological organic matter degradation for sediment rheology, contributing to an new definition of the nautical depth and to an improved management of sediments in ports and waterways. Further, I focus on the beneficial use of dredged material as construction material, e.g. in dikes, to achieve circular economy goals. A newly granted project will research methods to stabilise landfilled wastes to reduce future liability for society and create a sustainable environmentally safe situation.

My main research interests

Greenhouse gas release from riverine sediments
Beneficial use of dredged material
Stabilisation of wastes

I am looking for

Microbiology
Population analysis (DNA/RNA profiling)
Water chemistry

My expertise and technologies to offer

Microbial carbon turnover
Microbial methane oxidation
Biogeochemical soil ripening processes

CiTG
> Geoscience and Engineering
>> Geo-Engineering


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Jeroen Kalkman

About my work

I am fascinated by optical tomography and making cool imaging tools. My focus is on label-free imaging in 3D with optimal imaging performance (resolution, speed, and volume) and quantification of sample parameters. Besides a focus on quantitative zebrafish imaging, we also measure the composition of flowing (bio) suspensions,  biofilm growth, plant morphology, and tissue morphology.

My main research interests

Optical tomography
Optical signal processing
Zebrafish

I am looking for

Life scientists with challenging imaging problems

My expertise and technologies to offer

Optical tomography
Optical signal processing
Microscopy

TNW
> Imaging Physics
>> Kalkman Lab


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Valeria Garbin

About my work

I study soft and biological materials under flow and deformation, particularly the extreme deformation conditions of cavitation (high strain and high strain rate). Extreme deformation conditions due to cavitation are encountered at the tissue level for instance in blast traumatic brain injury; and at the cell level in bioprocessing. In my group we have developed experimental techniques to characterize the coupled fluid dynamics and soft/biological material deformation at high strain rates.

My main research interests

High-strain-rate deformation of soft/biological materials
Cell rupture due to ultrasound and cavitation
Mechanical phenotyping of cells in microfluidics

I am looking for

Microbiology
Bioprocessing
Tissue engineering

My expertise and technologies to offer

High-frequency rheology of soft materials (e.g. hydrogels)
Interfacial rheology (e.g. lipid or protein monolayers, lipid bilayers)
Ultrasound, cavitation and bubble dynamics

TNW
> Chemical Engineering
>> Transport Phenomena

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Amir Zadpoor

About my work

We develop biomaterials with impossible properties (meta-biomaterials) through advanced geometrical designs, multi-material 3D/4D printing techniques, and origami/kirigami methods. Biofabrication at different scales, shape-shifting biomaterials, and embedded functionality are at the core of our expertise. From the clinical viewpoint, we focus on the improved treatment of complex skeletal diseases including large bony defects, implant-associated infections, and multi-tissue lesions (e.g., osteochondral defects). Our ambition is to some day be able to print functional living materials and interface them with their non-living counterparts.

My main research interests

Bioprinting
Implant-associated infections
Soft robotics

I am looking for

Microbiology
Embedded printable electronics
Big data

My expertise and technologies to offer

3D/4D printing
Bioprinting
Surface bio-functionalization

3mE
> Biomechanical Engineering
>> Biomaterials and Tissue Biomechanics

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Angelo Accardo

About my work

The target of my research is to develop multi-scale (nano-micro-meso) 3D fabrication paradigms to address open questions in cell biology. I am interested in particular in the design and fabrication of 3D architectures by employing light-assisted additive manufacturing techniques (such as two-photon lithography and stereolithography). I plan to exploit the 3D engineered microenvironments for studying the mechanobiology and differentiation mechanisms of cells coming from different tissues (e.g. brain, bone) as well as the response of cancer cells to proton therapy.

My main research interests

3D Engineered Scaffolds
Neuroscience
Mechanobiology

I am looking for

Cell biologists
3D Imaging (e.g. two-photon confocal imaging, light sheet fluorescence microscopy)
Polymer/hydrogel chemists

My expertise and technologies to offer

3D microfabrication
Mechanical Nanoindenting
Scanning Electron Microscopy

3mE
> Precision and Microsystems Engineering (PME)
>> Micro and Nano Engineering

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Marcel Reinders

About my work

I initiated work on molecular classification and genetic network modelling. Nowadays, I focus on sequencing analysis tools, network-based analysis, and integration of genomic data. I have ample experience with finding gene signatures, for example with applications in cancer and neurodegenerative data.   

My main research interests

Relationship (large) structural variations and disease
Heterogeneity and its development/expansion of cell systems such as the immune system, brain cells or cancerous tissue
Solutions on how to integrate multiple molecular types as well as spatial and temporal data to unravel biological complexity

I am looking for

Single cell biology
Long-read sequencing-based biology
Molecular neuroscience

My expertise and technologies to offer

Tailored development of novel algorithms to analyse big and/or complex molecular data
Broad statistical and machine learning knowledge
High-performance computing infrastructure and solutions

EWI
> Intelligent Systems
>> Pattern Recognition and Bioinformatics

Visit Delft Bioinformatics Lab website 

Christophe Danelon

About my work

We are reconstituting a biological cell from its basic molecular constituents. The essential modules we are building are: a liposome compartment, gene expression, DNA replication, phospholipid synthesis and liposome division. We combine engineering methods with in vitro evolution to implement all modules into a self-replicating synthetic cell.   

My main research interests

In vitro evolution
Genome assembly
Mass spectrometry (proteomics, metabolomics)

I am looking for

Genome editing
DNA assembly technologies

My expertise and technologies to offer

Membrane biophysics
Cell-free gene expression
Liposome production

TNW
> Bionanoscience
>> Danelon Lab

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Hassan HosseinNia

About my work

I am interested in developing precision motion systems for high-tech as well as medical applications. My current research is twofold: 1) in development of industry standard, easy to use motion controller applying nonlinear strategies and 2) in development of integrated active metamaterial (soft actuator) for vibration damping in precision systems and for actuation in medical application.   

My main research interests

Precision robotics
Precision positioning systems
Precision control

I am looking for

Precision robotics
Abdominal assist device

My expertise and technologies to offer

Advanced motion control
Vibration control
Smart material actuator

3mE
> Precision and Microsystems Engineering (PME)
>> Mechatronic System Design

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Jie Zhou

About my work

I develop biodegradable materials for bone replacement, repair or bone tissue engineering. I am interested in understanding their degradation behaviour, changing mechanical performance and interactions with surrounding tissues and body fluids.    

My main research interests

Biodegradable metals and composites
Additive manufacturing

I am looking for

Experts in cyto-, histo- and hemocompatibility tests

My expertise and technologies to offer

Alloy design and fabrication technology
Forming technology
Powder technology

3mE
> BioMechanical Engineering
>> Biomaterials and Tissue Biomechanics

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Cees Dekker

About my work 

We employ single-molecule biophysics techniques to survey a variety of subjects from DNA loop extrusion and supercoiling to nanopore studies of nuclear pore complexes and protein sequencing. More recently, our research has focused on studying chromatin structure and cell division with bacteria on chip for synthetic cells.

My main research interests

Chromatin biology
Protein sequencing
Synthetic cells

I am looking for

Ultralong DNA
Chromatin-related proteins
Divisome proteins

My expertise and technologies to offer

Micro/nanofabrication
Single-molecule biophysics techniques

TNW
> Bionanoscience
>> Cees Dekker Lab

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Dimitra Dodou

About my work

My research aim is to develop adhesives and adhesive methods that allow for the effective manipulation of soft and wet biological tissue. In other words, my research is concerned with the study of interfacial phenomena between two bodies, where at least one of the two bodies is living, wet, soft, and vulnerable. 

My main research interests

Wet adhesion
Secure and gentle grip

I am looking for

Soft polymers
Stimuli-responsive polymers
Soft matter
Soft robotics

My expertise and technologies to offer

Adhesion
Soft-tissue grip
Experimental methods

3mE
> BioMechanical Engineering
>> Medical Instruments & Bio-Inspired Technology

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Ludovic Jourdin

About my work

I develop novel microbial electrochemical technologies for the bioproduction of chemicals, fuels, feed, and food from carbon-containing wastes (e.g. CO2) and renewable electricity. I particularly focus on bioreactor designs, fundamental understanding of mechanisms occurring at the electrode surface and within biofilms, process integration, and scale up. 

My main research interests

Chemicals bioproduction
Biofilms
Bioreactor design

I am looking for

Microbiologists
Material science experts
Modeling experts

My expertise and technologies to offer

Bioelectrochemistry
Electro-fermentation

TNW
> Biotechnology
>> Bioprocess Engineering

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Peter-Leon Hagedoorn

About my work

Certain enzymes have metals, and these metal gives them special powers. In order to understand these powers I have developed specific tools (MIRAGE, Nanospec) and use special techniques (calorimetry, EPR spectroscopy) to study these enzymes. This has allowed me to obtain very detailed understanding of the mechanism of action of these enzymes, e.g. the Fe2+ oxidation mechanism of the universal Fe storage enzyme ferritin. I am expanding this further, developing even better tools, studying novel enzymes and unlocking their secrets.

My main research interests

Enzyme discovery and engineering
Metalloproteomics in health and biotechnology
Uncovering enzyme mechanisms

I am looking for

Spectroscopy
Thermal imaging
Radionuclides
Metals in biology

My expertise and technologies to offer

Protein engineering, expression and purification
Electron paramagnetic resonance
Rapid mixing devices for pre-steady state enzyme kinetics

TNW
> Biotechnology
>> Biocatalysis

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Elizabeth Carroll

About my work

My lab uses interdisciplinary science and engineering approaches to develop optical imaging methods for the study of animal physiology. We design unique microscopes and novel biosensors that make it possible to combine multiple scales of spatial, temporal, and chemical resolution. With the tools we build, we address systems-level questions from neurobiology, immunology and toxicology using zebrafish as a small animal model. 

My main research interests

Neuro/endocrinology
Systems biology
Neuroscience

I am looking for

Molecular biology
Developmental biology
Neuroscience

My expertise and technologies to offer

Zebrafish
Light sheet microscopy
Optogenetics

TNW
> Imaging Physics
>> Zebrafish Development Lab

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Dimphna Meijer

About my work

My group aims to understand neural circuitry formation on the molecular and atomic level. We use a combination of molecular and cellular biophysics, such as single particle cryo-electron microscopy and high content confocal imaging, to understand how neurons form connections, also known as synapses. The assembly and disassembly of synapses is how we learn – and forget.

My main research interests

Protein Biochemistry
Biophysics of Neural systems
Brain Cancer and Neurodevelopmental disorders

I am looking for

Protein chemists
Electrical nanocircuits
In vivo imaging

My expertise and technologies to offer

Cell biology
Biochemistry (e.g. protein expression and purification)
Neuroscience (e.g. neurons in a dish)

TNW
> Bionanoscience
>> Meijer Lab

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Caroline Paul

About my work

Our current research interests are focused on the use of synthetic and orthogonal cofactors for oxidoreductase and transferase enzymes to catalyse chemical reactions, with an emphasis on the development of non-natural enzymatic reactions for applications in pharma- and fine chemical industries.

We are interested in exploiting the catalytic mechanism of enzymes, improving the overall robustness of the reaction, and targeting the synthesis of valuable compounds.

My main research interests

Enzyme-catalyzed reactions
Synthetic and orthogonal cofactors for enzymes

I am looking for

Other researchers open for collaborations!
Materials
Bioinformatics
Structural biology
Other

My expertise and technologies to offer

Biocatalysis
Synthetic organic chemistry

TNW
> Biotechnology
>> Biocatalysis

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Rienk Eelkema

About my work

Our research is concerned with the design, synthesis, characterization and application of new soft molecular materials. We have a special focus on using in situ chemical reactivity to control the assembly of dynamic materials and the stability of polymers, to make materials that can respond to changes in their environment and their application in drug release, and the selective functionalization of biomolecules.

My main research interests

Signal transduction in organic materials
Controlled release materials
Selective functionalization of biomolecules

I am looking for

Hybrid materials (living/non-living)
Functionalization of biomolecules
Healthcare materials

My expertise and technologies to offer

Synthetic organic chemistry
Self-assembly
Characterization of molecular structure and soft matter microstructures

TNW
> Chemical Engineering
>> Rienk Eelkema Lab

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Eduardo Mendes

About my work

My research focuses on the study of soft (responsive) matter, mainly gels and self-assembled structures and their interface with the living. Using techniques such as microfabrication, printing and microfluidics, I develop (gel) responsive particles or surfaces with potential use in therapy, tissue engineering and sensing (diagnosis).

My main research interests

Responsive gels
Cell behaviour/interaction with soft surfaces
Sensing

I am looking for

Cell biologists
Neuron experts
Immune system experts

My expertise and technologies to offer

Soft Matter processing and properties
Soft Matter characterization
Smart/responsive gels

TNW
> Chemical Engineering
>> Advanced Soft Matter

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Stephen Picken

About my work

I am an expert on polymer materials, in particular in the field of liquid crystal polymers and (bio)polymer nanocomposite based systems. My work is aimed at using modelling and structural characterization methods to elucidate the structure-property relations in such materials, including the dynamics during formation and in the final material.

My main research interests

(Bio)polymer nanocomposites
Dynamics
Structure-property relations

I am looking for

Biobased materials and applications

My expertise and technologies to offer

Structure formation and characterization
Thermal and solution processing
Designer materials

TNW
> Chemical Engineering
>> Advanced Soft Matter

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Mark van Loosdrecht

About my work

We study microbial ecology in engineered systems and design of processes for wastewater treatment and resource recovery based on the obtained knowledge. Our focus is on conversions of nitrogen and phosphate, biofilm systems, effect of dynamic process conditions and role of storage and extracellular polymers in microbial processes.

My main research interests

Biofilm and granular sludge processes
Extracellular polymers
Biological phosphate removal

I am looking for

Analysis and characterization of complex biopolymers
Bioinformatics

My expertise and technologies to offer

Microbial ecology
Process design

TNW
> Biotechnology
>> Environmental Biotechnology

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Santiago Garcia

About my work

My team focuses on understanding how dynamic polymers and bio based substances can be used to develop novel polymeric and hybrid materials for engineering applications. Our work is highly multidisciplinary and deals with a range of materials such as coatings, surface treatments and composites. Over the last years we have strongly specialized in developing characterization protocols to better describe the materials behaviour of self-healing/dynamic polymers, coatings and biological substances. 

My main research interests

Responsive coatings and composites
Novel materials from biological systems
Surfaces and interfaces

I am looking for
Biotechnologists to team up with.

My expertise and technologies to offer

Functional surfaces and interfaces
Polymer structure-property relationships
Materials characterization

LR
> Aerospace Structures and Materials
>> Novel Aerospace Materials 

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Raf van de Plas

About my work

Our lab focuses on the interface between three different fields: (i) mathematical engineering and machine learning; (ii) analytical chemistry and instrumentation physics; and (iii) life sciences and medicine. My research is specifically focused on the computational analysis of molecular imaging modalities such as imaging mass spectrometry and microscopy, and on the mathematical integration of information from different imaging technologies through data-driven image fusion.

My main research interests

Signal analysis & machine learning
Molecular imaging
Mass spectrometry

I am looking for

Molecular imaging applications
Big data imaging analysis problems
Computational analytical chemistry problems

My expertise and technologies to offer

Advanced signal analysis and machine learning methods for imaging
Image fusion between different imaging technologies
Imaging mass spectrometry

3mE
> Delft Center for Systems and Control
>> Numerics for Control and Identification (N4CI) 

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Stéphanie Cazaux

About my work

I am working with laboratory experiments to understand the formation and evolution of ices (and composition) in conditions similar to our early solar system. I am working on the plumes (crygesers) on icy moons of our solar system and if life could be present in such conditions and how it could be detected by future missions.

My main research interests

Ices formation, composition, complexity
Formation of the solar system (planets and moons)
Icy moons and sub-surface ocean

I am looking for

Microbiologists
Marine biologists
Surface chemists


My expertise and technologies to offer

Laboratory experiments
Models from laboratory to space

LR
> Space Engineering
>> Astrodynamics and Space Missions 

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Marlies Goorden

About my work

I am a physicist working on the development of new technologies and image reconstruction algorithms to improve radionuclide imaging (SPECT-PET). Together with industrial partners and academic medical centers I have developed high-resolution tomography for small experimental animals with unprecedented resolutions that can image radioisotopes with a very broad range of energies and in different combinations (multi-isotope imaging). Many of these scanners are currently in use by biomedical researchers world-wide. I am currently also applying our technologies to develop clinical scanners (to image patients). My expertise mainly lies in theoretical analysis of scanner geometries, optimization through simulations and development of new image reconstruction algorithms.

My main research interests

Radionuclide imaging
Image reconstruction
Scanner optimization

I am looking for

Biological and biomedical applications for radionuclide and CT imaging

My expertise and technologies to offer

Small animal SPECT
Small animal PET
MicroCT

TNW
> Radiation Science & Technology
>> Biomedical Imaging 

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Luis Portela

About my work

My research focus on complex engineering flows, in particular, involving multiphase flow and turbulence. I am interested in theoretical, numerical and experimental work. My work covers a wide range of topics, from fundamental studies on particle-laden turbulent flows, to  multiphase flows in (bio) chemical processes. I am interested in studying bio-reactors from an holistic perspective, combining the micro-organisms (genetic) aspects with the entire fluid transport processes.

My main research interests

Fluid Mechanics
Complex Systems
Phenomenological Modelling

I am looking for

Micro-organisms models
Micro-organisms genetics
Dynamics of biological systems

My expertise and technologies to offer

Fluid Mechanics
Numerical Methods
Experimental Techniques

TNW
> Chemical Engineering
>> Transport Phenomena
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Zoltán Perkó

About my work

My research focuses on novel radio- and proton therapy treatment planning approaches for cancer treatment. These include handling uncertainties (arising from e.g. patient positioning and proton range errors, breathing and organ motion), quantifying treatment robustness, developing robust optimization methods, optimizing radiotherapy fractionation and combined modality treatments, building decision support tools and exploring biology based treatment planning.

My main research interests

Biology based radiotherapy treatment planning
Robust/probabilistic proton therapy treatment planning
Uncertainty quantification method development

I am looking for

Bioinformatics
Radiobiology
In-vivo imaging

My expertise and technologies to offer

Treatment optimization
Numerical modelling
Sensitivity and uncertainty analysis

TNW
> Radiation Science & Technology
>> Reactor Physics and Nuclear Materials

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Daan Brinks

About my work

My lab addresses neuroscience questions through functional imaging. We develop tools with roots in physics, biochemistry, optics, mathematics and nanofabrication and we're interested in how brain cells work on every level, from biophysical principles to consequences in behavior and from subcellular compartments to complete organisms. Our main workhorses right now are Genetically Encoded Voltage Indicators, which we develop and apply.

My main research interests

Multiphoton voltage imaging
Functional nanoscopy
The role of bioelectricity in embryonic development

I am looking for

Protein evolution
Biostatistics
Genome editing

My expertise and technologies to offer

Nonlinear imaging
In vitro & In vivo functional imaging
Neuroscience

TNW
> Imaging Physics
>> The Brinks Lab 

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Wiebren de Jong

About my work

I develop processes for the conversion of biomass/waste possibly integrated with energy storage via electrolysis (CO2, water). In the group we perform process system design modelling work as well as experimental development and testing of key components in integrated systems.

My main research interests

Energy storage concepts
Biorefinery
CO2 capture and utilization

I am looking for

Process system integration
Biorefinery
Energy storage

My expertise and technologies to offer

Process system design and modelling
Bioresources characterization
Fuel conversion testing

3mE
> Process and Energy
>> Large-Scale Energy Storage

 

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Doris van Halem

About my work 

We focus on drinking water treatment for global development, with an emphasis in filtration systems for groundwater and household water treatment. Specific examples of research projects are subsurface arsenic removal, biological As(III) oxidation in rapid sand filters, virus removal with low-cost ceramic membranes and safe reuse of water in urban areas.

My main research interests

Removal of geogenic contaminants (arsenic, fluoride, manganese)
Clever drinking water solutions for global development

I am looking for

Engineering microbial communities in low nutrient and fast-flowing systems
Antibiotic resistance (genes, bacteria) in water treatment
Biofilm characterisation methods

My expertise and technologies to offer

Arsenic and iron removal (linking bio to chemical-physical)
Household water treatment for disinfection
Field research in developing countries

CiTG
> Water Management
>> Staff Sanitary Engineering


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Pouyan Boukany

About my work

My group focuses on fundamental and applied topics in soft living matter, with a major emphasis on controlling and understanding the dynamics and transport of DNA into living cells. To do this, we apply cutting-edge micro/nano-fluidic technologies to manipulate and control the DNA and biomolecules for both fundamental biophysical studies and applications, such as non-viral gene therapy, biosensing and cancer therapy.

My main research interests

Biophysics
Cell membrane
Molecular crowding

I am looking for

Cell Biology
Surface modification
High resolution imaging

My expertise and technologies to offer

Non-viral gene/drug delivery
Microfluidics
Single-cell/DNA manipulation

TNW
> Chemical Engineering
>> Product and Process Engineering


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Merle de Kreuk

About my work

I am Professor of Environmental Technology at the CITG department of water management. I focus on granular sludge processes (aerobic and anaerobic) and (pre)hydrolysis in these systems as well as in anaerobic digestion. Enzymatic (hydrolytic) activity, mixing processes and effect of recalcitrant and inhibiting compounds in these systems are focus points.

My main research interests

Hydrolysis of complex substrates
Granule formation
Formation of products from wastewater 

I am looking for

Enzymes (activity)
Microbiology (bio-informatics)
Computational Fluid Dynamics (CFD) 

My expertise and technologies to offer

Anaerobic digestion processes
Granular sludge for sewage treatment
Process design

CiTG
> Water Management
>> Sanitary Engineering


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Albert van de Wiel

About my work

Our work concerns the application of both stable and radioactive isotopes in clinical medicine. I focus on stable isotopes, my colleague Antonia Denkova on radioactive isotopes.

My main research interests

Multi-element analysis in human material
Application of enriched stable isotopes in clinical research
Radionuclides in diagnostic procedures

I am looking for

Opportunities for collaboration

My expertise and technologies to offer

INAA
Radiochemistry
Contacting clinical researchers

TNW
> Radiation Science & Technology
>> Applied Radiation and Isotopes


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Daniel Tam

About my work

Our group investigates the dynamics of active biological fluids involving self-propelled particles. We want to elucidate the origins of the collective behavior observed in many of these dense suspensions (from micro-algae to fish), with the goal of controlling and harnessing this self-generated motion. We use tools from experimental fluid dynamics to track and characterize the dynamics.

My main research interests

Biological Fluid mechanics
Wet-Soft-Complex-Active matter (!)
Microfluidics

I am looking for

Algae-based bio-process technology
Microfabrication for microfluidics (electro-osmosis)
Cell biology

My expertise and technologies to offer

Optical flow diagnostic
3D-optical tracking of microparticles
Fluid mechanics

3mE
> Process & Energy
>> Fluid mechanics


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Alexis Bohlin

About my work

Advances in optical imaging techniques over the past decades have revolutionized our ability to study living systems at the microscopic level. Emerging technology for unravelling chemical composition in systems of cellular and molecular biology provides a major asset in research and industrial applications. We develop new frontiers in optical coherent Raman imaging tailored at biofuel production- and renewable aero propulsion systems.

My main research interests

Renewable fuels for air transportation
Reduced emission of pollutants
Ultrafast laser diagnostics

I am looking for

In-situ thermometry applications
Microbial production of biofuels
Microfluidics  

My expertise and technologies to offer

Coherent Raman imaging
Time-resolved spectroscopy
Chemical detection and sensing 

LR
> Aerodynamics, Wind Energy & Propulsion
>> Flight Performance and Propulsion


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Elvin Karana

About my work

My research aims to understand and enhance the relationships people have with the materials of products. I have undertaken this topic with a holistic approach, capitalizing on not only the technical properties of materials, but also meanings, emotions and actions materials in products elicit. 

My main research interests

Material Driven Design
Appreciation of Materials
BioBased Materials

I am looking for

Novel bio-based materials
Waste-based materials
Materials scientists who are interested in design collaborations

My expertise and technologies to offer

Experiential characterization of materials
Bridging technical and experiential qualities
Transition of materials into consumer products

IO
> Design Engineering
>> Emerging Materials


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Stan Brouns

About my work

We are interested in the interaction between microbes and viruses and studies the mechanisms that bacteria and archaea use to protect themselves from virus infection including CRISPR. My lab explores the adaptations that viruses have evolved to avoid defense systems and engineers bacteriophages for phage therapy applications.

My main research interests

Bacteria
CRISPR
Bacteriophage biology and therapy

I am looking for

Bioinformatics
Microfabrication
Microbiology

My expertise and technologies to offer

Microbiology
Virology
Genetic/Genome engineering (CRISPR/Cas9)

TNW
> Bionanoscience
>> Brouns Lab


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Chirlmin Joo

About my work

Using cutting-edge single-molecule fluorescence tools, we investigate how small RNA mediates gene silencing (RNA interference) and anti-viral defense (CRISPR immunity and DNA interference). We apply the mechanistic understanding to genome editing. Furthermore, we develop single-molecule protein sequencing techniques for advanced proteomics analysis.

My main research interests

Small regulatory RNA
CRISPR bacterial immunity
Single-molecule proteomics

I am looking for

I am open to explore opportunities for collaboration.

My expertise and technologies to offer

Single-molecule fluorescence (FRET)
Low light imaging
Optical tweezers (cell manipulation and force sensing)

TNW
> Bionanoscience
>> Chirlmin Joo Lab


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Duncan McMillan

About my work

The Membrane Bioenergetics Unit (MBU) is headed by Assistant Professor Dr Duncan McMillan and is based in the Department of Biotechnology (Biocatalysis Group). The overarching theme of the research of the MBU is focused on ‘energy and life’ exploring microbial physiology using classical microbiology and biochemistry, biomimetic membrane technologies and single-molecule biophysics. With this fundamental knowledge we investigate the adaptations of life to selective environmental pressures with particular focus on the function of the cell membrane, and the role of respiratory enzymes in health and disease.

My main research interests

Regulation and function of respiratory chain components 
The role of metals in respiratory enzymes and their function in electron transfer
Protein-protein and protein-lipid interactions
Biomechanics of molecular motors

I am looking for

Microbiologists
Nanofabrication
Surface chemists

My expertise and technologies to offer

Biochemistry of membrane/soluble proteins
Enzyme kinetics
Biomimetic membranes
Bioelectrochemistry
Impedance spectroscopy
Molecular motors

TNW
> Biotechnology
>> Biocatalysis


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Marie-Eve Aubin-Tam

About my work

I am interested in the interplay between structure and mechanics in biological molecules and materials. I have two main lines of research: (i) the study of mechanical processes at the cell membrane, and (ii) the production of biomineralized composite materials. 

My main research interests

Biomimetic materials
Cell membrane mechanics
Protein conformational dynamics

I am looking for

Crystal formation
Polymers
Materials characterization

My expertise and technologies to offer

Microfluidics
Optical tweezers
Biophysics

TNW
> Bionanoscience
>> Aubin-Tam Lab


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Timon Idema

About my work

We study collective dynamics in biological and biomimetic systems, ranging in scale from proteins to populations. On the molecular scale, we study self-assembly in realistic (crowded) environments to get a handle on dynamical processes like cellular signaling, cell motility, and cell division. On the population scale, we investigate how tissues and biofilms form, how they can be influenced, and how they respond to perturbations.

My main research interests

Collective dynamics
Protein interactions
Active matter

I am looking for

Cell biologists
Experimental biophysicists

My expertise and technologies to offer

Theoretical modeling of (bio)physical systems

TNW
> Bionanoscience
>> Idema Group


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Marie-claire ten Veldhuis

About my work

My work focuses on using observational datasets to analyze and predict how hydrological systems respond to (extreme) rainfall and drought. Recently, I have become interested in studying hydrology at the nano-scale, looking into water transport in lichens, a fungus-algae symbiosis. I’m interested in understanding how water transport is regulated by lichen architecture and more generally in plants to quantitatively model water transport in relation to photochemistry (water oxidation).

My main research interests

Hydrometeorology
Smart sensing
Citizen science

I am looking for

In-vivo imaging
Microfluidics
In-vivo measurement of water potential/pressure dynamics

My expertise and technologies to offer

Hydrology
Rainfall variability
Water systems engineering 

CiTG
> Water management
>> Water Resources Group


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Jules van Lier

About my work

My research projects focus on closing water cycles in industries and sewage water recovery for industrial or agricultural reuse. I am specialized in Anaerobic Treatment Technology and I received both my MSc and PhD from Wageningen University. I am full professor “Wastewater Treatment/Environmental Engineering” at the section Sanitary Engineering of CiTG, with a 0,2 fte seconded position at UN-IHE, Delft.  

My main research interests

Bio-technologies for (waste)water treatment, from both municipal and industrial origin
Anaerobic treatment (conversion processes) for wastewater, sludges and slurries
Sludge bed systems, (anaerobic) MBR systems 

I am looking for

Microbial functionality in complex systems

My expertise and technologies to offer

Mixed microbial processes for environmental engineering
Anaerobic conversion processes (microbiology, technology)
(Waste)water treatment in general

CiTG
> Water management
>> Sanitary Engineering


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Massimo Mastrangeli

About my work

I am developing microfabricated fluidic devices for cell cultures, based on silicon and polymers and integrating sensors and actuators, to realistically recapitulate the microphysiology of human tissues and organs – we call them microphysiological systems, or organs-on-chip. I am also interested in colloid-based bottom-up assembly of nanodevices, self-organization at all scales and soft microrobotics.

My main research interests

Microphysiological systems (MPSs)
Bottom-up assembly of nanodevices
Fluidic self-assembly 

I am looking for

Cell biologists
Polymer chemists
Plasmonics and optical metamaterials 

My expertise and technologies to offer

Surface tension effects
Self-assembly
Micro/nanofabrication & Microrobotics

EWI
> Microelectronics
>> Electric Components, Technology and Materials


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Arjen Jakobi

About my work

We study the structure and function of biomolecular machines. Biomacromolecules adopt intricate three-dimensional arrangements that are critical to their function. We are interested in the molecular mechanisms by which cells defend themselves against infection. Our research uses electron imaging methods to visualize the macromolecular complexes involved in these processes, and applies biochemical and biophysical tools to dissect their mechanism of action.

My main research interests

Electron cryo-microscopy (cryo-EM) and X-ray crystallography
Structural Biology of pathogen infection
Molecular mechanisms of biomacromolecular machines

I am looking for

Micro/nanofluidics
Machine learning
Image processing
Bioinformatics

My expertise and technologies to offer

Electron microscopy
Protein crystallography
Structural biology

TNW
> Bionanoscience
>> Jakobi Lab


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Burak Eral

About my work

I focus on understanding the fundamental out-of-equilibrium manufacturing/separation processes involving flow, phase transitions (particularly crystallization) and soft matter/complex fluids. Our approach is to understand how structure/dynamics of soft matter (hydrogels, emulsions, surfactants) and flow can be leveraged to dictate molecular phenomenon (polymorphism, crystallization, phase separation) and, ultimately, harness this understanding to rationally design functional materials and processes. 

My main research interests

Soft matter
Crystallization
Hydrodynamics

I am looking for

Human cell line culturing know-how
Biomineralization
Gut bacteria

My expertise and technologies to offer

Crystallization
Microfluidics
Soft matter

3mE
> Process & Energy
>> Intensified Reaction & Separation Systems


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Carlas Smith

About my work

There is an urgent need for high-throughput, high-resolution, live-tissue imaging to effectively study the origin, progression, and treatment of human diseases. I take a synergistic approach that considers optics and information aspects together to maximize the recorded information content of a microscope. The technology developments target single-molecule imaging with nanometer-resolution in live-thick tissue.

My main research interests

Super-resolution
Single molecule kinetics (CoSMoS)
Computational imaging

I am looking for

Bio-applications for super-resolution microscopy
Bio-applications for single-molecule imaging
Bio-applications for biophysics

My expertise and technologies to offer

Super-resolution microscopy
Single molecule imaging
Advanced stochastic signal analysis

3mE
> Delft Center for Systems and Control
>> Numerics for Control & Identification


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Liedewij Laan

About my work

My group focusses on evolutionary cell biophysics: how do the self-organisational (physical and chemical) properties of proteins affect the evolutionary dynamics of a biomolecular network? Mostly because it’s fascinating, but also to contribute to research on evolutionary processes relevant for human health, such as cancer progression. We combine experimental evolution and quantitative cell biology in yeast, minimal synthetic systems, reaction-diffusion based modelling and bioinformatics.

My main research interests

Evolutionary biology
Biophysics
Pattern formation

I am looking for

Bioinformatics
Microbial ecology 

My expertise and technologies to offer

Minimal reconstituted protein systems
Experimental evolution
Yeast cell biology

TNW
> Bionanoscience
>> Laan Lab


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Aljoscha Wahl

About my work

Metabolism is the ‘engine’ of microbial live, generating energy redox equivalents and precursors for growth. Its sustained operation by networks of enzymatic reactions forms a complex network that requires fine-tuned regulation. Identifying the underlying kinetics and understanding the regulatory mechanism of metabolism is our aim. We perform microbial experiments in controlled bioreactor environments, design and perform tracer experiments (13C carbon tracing) and kinetic modeling for industrial but also environmental microorganisms. 

My main research interests

Microbial cells
Systems biology
Biofuels

I am looking for

Membrane proteins
High performance computation
Single cell approaches

My expertise and technologies to offer

Systems biology
Metabolite analytics
Dynamic modelling

TNW
> Biotechnology
>> Cell Systems Engineering


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Joana Goncalves

About my work

I develop algorithms for pattern discovery in large-scale molecular biology data. Specifically, I am interested in understanding gene regulation dynamics and disruptions involved in disease to discover new therapeutic targets. I focus on pathway effects by integrating genetic variants (DNA), gene expression (RNA) and regulatory landscape including TF binding, epigenetic marks (ChIP) and chromatin organization (Hi-C). Also interested in perturbation data (CRISPR, si/shRNA).

My main research interests

Gene regulation
Time series
Cancer

I am looking for

Single-cell time series
Gene editing 
Molecular pertubation data

My expertise and technologies to offer

Data analysis
Pattern recognition
Machine learning

EWI
> Intelligent Systems
>> Pattern Recognition and Bioinformatics

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Martin Depken

About my work

I am a theoretical biophysicist specializing in using mathematical/physical modeling to understand how biological function arises from the interactions between molecular components. Of particular interest are the machines that process the information stored in our genomes, and the work is often performed in close collaboration with experimenters.

My main research interests

Transcription
Crispr-CAS
Method development for single-molecule data analysis

I am looking for

Bioinformatics

My expertise and technologies to offer

Theoretical modelling of microscopic phenomena

TNW
> Bionanoscience
>> Depken Group

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Ralph Lindeboom

About my work

Both Space and the deep sea offer interesting opportunities for exploring the boundaries of life. Particularly microbial life in hydrothermal vents provides me with the inspiration to develop novel bio-thermochemical resource recovery concepts from (waste-) water. By frugalizing advanced technological solutions in the bioprocess and thermochemical domains, and isolating specialized microbes from extreme environments, I aim to add value to residual streams in the developing world. 

My main research interests

Decentralized resource recovery concepts
High pressure anaerobic digestion
Solar thermochemistry
Frugal engineering

I am looking for

Thermochemical biomass processing experts
Optics experts
Environmental microbiologists

My expertise and technologies to offer

High pressure biotechnology
Closed Loop Life Support Engineering
Wastewater treatment
Biogeochemistry

CiTG
> Water Management
>> Sanitary Engineering

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Antonia Denkova

About my work

My research focuses on the development of radionuclide therapy for cancer treatment aiming at decreasing collateral damage while maximizing tumor damage. The research consists of determining the best radioisotope depending on the tumor characteristics, optimizing the production of these radioisotopes, developing methods to bring these radioisotopes to the targeted area and final evaluation in vitro and in vivo.

My main research interests

Radiation effects on cells
Development of delivery systems for radioisotopes
Neutron activation of different compounds including chemotherapeutics

I am looking for

Imaging in vitro
Bioassay development
Microfluidics

My expertise and technologies to offer

Preparation of radiotraces for life science experiments
In vitro evaluation 2D and 3D
Soft matter nano-systems loaded with chemotherapeutics or radionuclides

TNW
> Radiation Science & Technology
>> Applied Radiation and Isotopes 

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Greg Bokinsky

About my work

We are curious to learn how bacteria work, and in figuring out ways to make bacteria (even more) useful. We have both fundamental and applied projects, and are always happy to pursue research in new and interesting directions.

My main research interests

Engineering antibiotic production in E. coli (yes, it does work)
Growth-rate regulation in bacteria
Genome mining for iron-sulfur cluster enzymes and cofactors in biotechnology

I am looking for

Bioinformaticists
Biochemists
Synthetic chemists

My expertise and technologies to offer

Bacterial physiology
Metabolic engineering
Synthetic biology

TNW
> Bionanoscience
>> Bokinsky Lab 

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Thomas Abeel

About my work

I am interested in developing algorithms and visualizations to answer questions in (micro-)biology. Particularly, I am interested to accurately reconstruct the complex heterogeneous genome and transcriptome architectures found in microbial organisms in the medical and industrial domain. The goal is to link genotypes to observed changes in molecular and extended phenotypes of medical or industrial importance, such as antibiotic resistance, virulence or product yield.

My main research interests

Microbial genomics
DNA sequence analysis algorithms
Genomics visualization

I am looking for

Microbial genomics and microbial genomics projects involving DNA, RNA sequencing and other -omics datatypes for integration.

My expertise and technologies to offer

High performance computing: ~1000 CPU cluster + supporting infrastructure
Bioinformatics for DNA/RNA sequence analysis: variant calling, expression, statistics, machine learning, comparative genomics, etc.
Oxford Nanopore Technologies sequencing: long-read sequencing

EWI
> Intelligent Systems
>> Pattern Recognition and Bioinformatics

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Ivan Buijnsters

About my work

The focus of my research is the development of diamond-based functional surfaces and nanomaterials for micro and nano engineering applications. In particular, I work on the synthesis, characterization and application of diamond thin films and nanoparticles for application in (photo)catalysis, electrochemical biosensing, tribology, and water treatment.

My main research interests

Carbon nanomaterials, particularly diamond
Materials synthesis
Surface engineering

I am looking for

Biochemists
Water/wastewater engineers
Surface chemists

My expertise and technologies to offer

Tailored diamond materials (e.g. thin-film electrodes, nanoparticles)
Thin film deposition
Materials characterization

3mE
> Precision and Microsystems Engineering

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Michel Verhaegen

About my work

I am interested in retrieving mathematical models of dynamical systems from excitation-response measurements retrieved in dedicated system identification experiments. Current interest focuses on the identification of spatial-temporal dynamical systems with a large number of actuators and sensors.

My main research interests

Numerical method development for identification of large scale systems
Sensor array networks and control for high resolution imaging 

I am looking for

Large scale network identification and control problems
High resolution imaging applications with BioData

My expertise and technologies to offer

World class research in System Identification and Control

3mE
> Delft Center for Systems and Control
>> Numerics for Control and Identification

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Martin Pabst

About my work

We are performing research on microbial protein modifications which are utilised to regulate important functions of a cell like for modulating enzyme activities in metabolic pathways. The focus thereby is on cell systems with relevance for industrial applications. Furthermore, we are interested in exploring how microbes work together by characterising biofilm components such as proteins and carbohydrates using meta-proteomics approaches.

My main research interests

Post-translational protein modifications
Bacterial communities
High-resolution and quantitative mass spectrometry

I am looking for

Bioinformatics
Fluorescence imaging
Statistics

My expertise and technologies to offer

High-resolution and quantitative mass spectrometry
Protein chemistry
Proteomics

TNW
> Biotechnology
>> Cell Systems Engineering

Webpage under construction
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Murali Ghatkesar

About my work

I am interested in developing micro and nanoscale devices for quantification in biology and chemistry. I use a range of micro and nano fabrication techniques to make these devices. Some of my activities are: pipetting femto-liter volumes of fluid from individual cells, weighing mass of single cell objects and measuring elastic properties of soft objects.  

My main research interests

Micro and Nano fabrication
Micro and nano fluidics
Biophysics 

I am looking for

Single cell biologists
Biophysicists
Biochemists

My expertise and technologies to offer

Micro and nano fabrication
Single cell biopsy
Atomic force microscopy

3mE
> Precision and Microsystems Engineering

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