Innovation is crucial to fulfil the potential of industrial biotechnology for sustainable production of fuels, chemicals, materials, food and feed. Similarly, scientific and technological advances in environmental biotechnology are needed to enable novel approaches to water purification, and ‘waste-to-product’ processes thus contributing to a circular economy. Increased fundamental knowledge encompassing enzymes, microorganisms and processes are essential for progress in this field. The Department of Biotechnology covers this research area and, based on new insights, selects, designs and tests new biobased catalysts, micro-organisms, and processes.
The department encompasses five research sections:
15 April 2022
National Growth Fund finances Cellular AgricultureThe National Growth Fund of the Dutch government grants conditional funding of 60 million euros to the Cellular Agriculture consortium, whose goal is to produce and promote protein-rich food from cultivated cells. The TU Delft is one of the founders of the consortium, with Marcel Ottens as initiator of the line of research. The TU Delft, together with the companies PlanetBio, DSM, Meatable, CE Delft and others, forms a hub in Delft for this new field of work.
24 February 2022
Mark van Loosdrecht wins Novozymes Prize for 25 years of revolutionary wastewater treatmentThe development of new technologies for biological wastewater treatment is turning our view of sludge upside down. Microbiologist Mark van Loosdrecht receives the 2022 Novozymes Prize for his pioneering work in copying and reusing nature’s mechanisms in wastewater treatment and resource recovery. Van Loosdrecht: “Treating wastewater will become good business in the future.”
23 December 2021
Super-fast technique measures heme enzyme reaction as it happensResearchers from TU Delft found an unexpected new enzyme intermediate at work in enzymes that contain heme, a cofactor that’s vital for many processes in our body such as the breaking down of toxins in the liver. The researchers used new, rapid techniques, which are less invasive than existing methods. The results, published in ACS Catalysis, increase our understanding of heme proteins and enzymes and how they can be engineered.
28 May 2020
Awards for three researchers of ASIt's raining awards at the Faculty of Applied Sciences. No less than three researchers have been rewarded with various prizes over the past period. They are Ad van Well, Arthur Gorter de Vries and Jasmijn Hassing. Together with colleagues from 3mE, Ad van Well (Radiation Science & Technology) received the Vanadium Award for the best scientific article of 2019 in the fiel of vanadium research . The award is presented by the Institute of Materials, Minerals and Mining (IOM3) in Great Britain. The article stems from the HTM/NWO Nano-steel project, in which Ad van Well and his colleagues, especially PhD candidate Chrysoula Ioannidou, are researching a new type of steel that is both strong and malleable: pure ferrite reinforced with nanoparticles of vanadium carbide. Ex-researcher A rthur Gorter de Vries (Biotechnology) received the Westerdijk Award for the best dissertation of the year in the category Environmental & Applied Microbiology . This award is presented by the Royal Dutch Society for Microbiology (KNVM) and the Dutch Society for Medical Microbiology (NVMM). Gorter de Vries was frequently in the news before his promotion, among other things because he witnessed the emergence of a new gene in the lab and because of his discovery that all pilsner yeasts, the famous microorganisms that brewers produce hundreds of billions of litres of lager and other lager beers with every year, were created some 500 years ago in a one-off encounter between two types of yeast . Jasmijn Hassing, like Gorter de Vries from the group of Jean-Marc Daran (Biotechnology), received the Kiem Award. This prize is also awarded by the KNVM/NVMM, and is intended for excellent papers in which starting young microbiologists are the first authors. In order to qualify, the article must have been published in an internationally renowned journal in the past year. Hassing was awarded the prize for a paper on the production of 2-phenylethanol using yeast. 2-phenylethanol is an organic, aromatic compound that smells like roses and is widely used in the food and cosmetics industries.
14 May 2020
How copper can damage a cellCopper is important for many processes in our body. Among other things, it supports the production of red blood cells, metabolism, and the formation of connective tissue and bones. Copper is also known to play a role in diseases such as cancer, diabetes and Alzheimer's disease. Unfortunately, we do not yet know exactly what that role entails. Researchers from Delft University of Technology and the Polish Academy of Sciences have now discovered a new piece of the puzzle. In order to be able to do its work, copper binds to different types of proteins in the cell. And although the complexes that are formed in this process are not harmful in themselves, temporary 'intermediate forms' appear to arise during the binding, which can lead to damage to the cell. The results of the research have been published in Angewandte Chemie.
30 April 2020