Imaging Physics

     

The Department of Imaging Physics (ImPhys) focuses on developing novel, sometimes revolutionary, instruments and imaging technologies. These research products extend existing boundaries in terms of spatial resolution, temporal resolution, and information/data throughput. We are pioneers in developing advanced concepts of computational imaging, a marriage between cleverly designed imaging systems and sophisticated post-processing. 

ImPhys’s profile encompasses a mix of science, engineering and design. While the spectrum of imaging physics is very broad, we focus on a few key fields where we generate impact: Life sciences, Healthcare and High tech industry.

Imaging Physics

The Department of Imaging Physics (ImPhys) focuses on developing novel, sometimes revolutionary, instruments and imaging technologies.

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These research products extend existing boundaries in terms of spatial resolution, temporal resolution, and information/data throughput. We are pioneers in developing advanced concepts of computational imaging, a marriage between cleverly designed imaging systems and sophisticated post-processing. 

ImPhys’s profile encompasses a mix of science, engineering and design. While the spectrum of imaging physics is very broad, we focus on a few key fields where we generate impact: Life sciences, Healthcare and High tech industry.

Latest News

05 december 2016

Alberico Sabbadini joined our group as PhD student

Alberico started his PhD on 1 December. He will work on a method for early diagnosis of stiffening of the heart, which employs non-invasive ultrasound imaging and allows early identification of (patients at risk of developing) heart failure. The new method is based on the natural shear waves in the heart muscle, which find their origin in the natural “noise-like” mechanical excitations caused by the beating heart, flowing blood, breathing, etc. The propagation velocity of the resulting natural shear waves is dependent on the local stiffness of the heart muscle.

30 november 2016

NWO ECHO Project Jacob Hoogenboom approved

Title: "Optimized electron-molecule interactions for near-molecular resolution light and electron microscopy". The researchers propose a novel approach: fluorescence microscopy using a beam of energetic electrons. This will allow measuring molecular positions in the structural landscape at electron microscopy resolution. Their approach is enabled by two unconventional steps: (i) Fluorescent molecules will be excited in an electron microscope using low-energy (1-50eV) electrons, probing resonant and near-resonant intramolecular excitation regimes. (ii) Encouraged by recent initial observations of electron-excited fluorescence from green fluorescent protein (GFP) under vacuum, will optimize fluorescent proteins for fluorescence microscopy with focused electron beams. Thus, we will enable electron-excited fluorescence from organic fluorescent molecules commonly used as bio-molecular labels for immuno-targeting, as well as from optimized fluorescent proteins.

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